Alpa-Xylogel 2% Jelly is a specialized topical anesthetic formulation containing 2% Lidocaine hydrochloride. This viscous jelly provides effective local anesthesia for mucous membranes and sensitive tissues.
Uses
Alpa-Xylogel 2% Jelly is used to numb mucous membranes prior to medical procedures including urethral catheterization, cystoscopy, proctoscopy, endotracheal intubation, and gastrointestinal endoscopy. It also relieves pain from minor burns, cuts, insect bites, sore throat, mouth ulcers, and hemorrhoids.
Benefits
- Fast-acting local anesthetic effect
- Reduces pain and discomfort during medical procedures
- Minimizes gagging reflex during endoscopic procedures
- Lubricating properties enhance instrument insertion
- Water-soluble and easily washed away
- Non-irritating to sensitive tissues
- Compatible with mucous membranes
- Convenient jelly formulation for precise application
How It Works
Alpa-Xylogel 2% Jelly works by temporarily blocking nerve signals in the area where it is applied. Lidocaine inhibits sodium ion channels in nerve cell membranes, preventing the initiation and conduction of pain signals to the brain.
Duration of Action
Effects typically begin within 5-15 minutes after application. Local anesthetic effects generally last 20-30 minutes on mucous membranes, with variable duration depending on application site, tissue vascularity, and individual factors.
Dosage
| Application Site | Recommended Amount | Duration Before Procedure |
|---|---|---|
| Urethral procedures | 5-10 ml (male), 3-5 ml (female) | 5-10 minutes |
| Oral/pharyngeal | Thin layer as needed | 2-5 minutes |
| Rectal/proctoscopy | 5-10 ml | 5-10 minutes |
| Surface wounds/burns | Thin layer | Apply as needed |
Warnings
Do not use on large areas, open wounds, or broken skin. Avoid contact with eyes. Use caution in patients with severe liver disease, heart block, or known sensitivity to amide-type local anesthetics. Excessive use or ingestion may lead to systemic toxicity in rare cases.
Side Effects
Most users experience minimal side effects. Possible reactions include temporary local burning sensation, stinging, tenderness, swelling, or tissue irritation. Rare systemic effects may include dizziness, drowsiness, confusion, or cardiac symptoms with excessive absorption.
Pregnancy and Breastfeeding
Alpa-Xylogel 2% Jelly should be used during pregnancy only when clearly needed. Lidocaine passes into breast milk in small amounts. Nursing mothers should consult their healthcare provider before using this medication.
Interactions
- Antiarrhythmic medications (increased cardiac effects)
- Beta-blockers (potential increased lidocaine levels)
- Cimetidine (may increase lidocaine blood levels)
- Phenytoin (altered metabolism of lidocaine)
- Other local anesthetics (increased risk of systemic toxicity)
- Class III antiarrhythmics (increased cardiac risk)
- Mexiletine (additive effects)
Precautions
Apply only to intended areas. Avoid ingestion. Use the minimal effective amount. Do not exceed recommended dosage. Avoid food consumption immediately after oral application to prevent choking. Monitor for allergic reactions. Medical supervision required for extensive or repeated use.
Important Information
Alpa-Xylogel 2% Jelly is for topical use only. The numbing effect may impair protective reflexes, so avoid eating, drinking, or chewing gum within one hour of oral/throat application. Keep out of reach of children. Store at room temperature away from direct heat and light.
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