Amlozaar Tablet combines two powerful antihypertensive medications: Losartan (50mg) and Amlodipine (5mg). This fixed-dose combination tablet effectively treats high blood pressure through dual mechanisms of action. Developed for adults with hypertension, it offers convenient once-daily dosing for improved blood pressure management.
Uses
Amlozaar is primarily prescribed for treating essential hypertension in adults. It’s particularly effective for patients who haven’t achieved optimal blood pressure control with single-drug therapy. The medication also helps reduce cardiovascular risks associated with high blood pressure and provides protection against organ damage.
Benefits
- Effectively lowers both systolic and diastolic blood pressure
- Reduces risk of cardiovascular complications
- Provides 24-hour blood pressure control
- Improves medication adherence through once-daily dosing
- Protects against organ damage from hypertension
- Reduces peripheral edema compared to high-dose amlodipine alone
- Cost-effective compared to taking components separately
- Better tolerability than maximum doses of individual components
How It Works
Losartan blocks angiotensin II receptors, reducing blood vessel constriction and decreasing blood pressure. Amlodipine, a calcium channel blocker, relaxes blood vessels and reduces peripheral resistance. This dual action provides comprehensive blood pressure control through complementary mechanisms.
Duration of Action
Amlozaar Tablet typically starts working within 2 weeks, with full therapeutic effect achieved within 4-6 weeks. The combination provides 24-hour blood pressure control with once-daily dosing. Regular monitoring is essential to ensure optimal effectiveness.
Dosage
Standard adult dose is one tablet daily, preferably at the same time each day. Can be taken with or without food. Dose adjustments should only be made under medical supervision based on blood pressure response.
Side Effects
Common side effects of Amlozaar Tablet include dizziness, headache, mild ankle swelling, and fatigue. These typically improve as your body adjusts to the medication. Most side effects are mild and transient.
Warning
Discontinue use and seek immediate medical attention if experiencing angioedema, severe dizziness, fainting, or chest pain. Regular blood pressure monitoring is essential. Not recommended for patients with severe liver impairment.
Pregnancy and Breastfeeding
Contraindicated during pregnancy as it can cause fetal harm, particularly in the second and third trimesters. Not recommended during breastfeeding. Women of childbearing age should use effective contraception while taking this medication.
Interactions
- NSAIDs may reduce the antihypertensive effect
- Potassium supplements may increase potassium levels
- CYP3A4 inhibitors may increase amlodipine levels
- Lithium levels may be affected
- Other blood pressure medications may enhance effect
Important Information
Store below 30°C in a dry place. Monitor blood pressure regularly. Report any significant side effects to your healthcare provider. Don’t stop taking suddenly without medical advice. Have regular kidney and potassium level checks. Take missed doses as soon as remembered, unless it’s almost time for the next dose.
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