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Avicef Injection 1g (Ceftriaxone)

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Avicef Injection is used to treat a wide range of bacterial infections, including lower respiratory tract infections, urinary tract infection,s and gonorrhea

4,000.00

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Avicef Injection 1g contains ceftriaxone, a third-generation cephalosporin antibiotic. This potent medication offers broad-spectrum activity against many gram-positive and gram-negative bacteria. Avicef is designed for intravenous or intramuscular administration, providing rapid and effective treatment for various bacterial infections.

Uses

Avicef Injection is primarily used to treat a wide range of bacterial infections, including:

  • Lower respiratory tract infections
  • Urinary tract infections
  • Gonorrhea
  • Skin and soft tissue infections
  • Bone and joint infections
  • Meningitis
  • Intra-abdominal infections
  • Septicemia
  • Surgical prophylaxis

Benefits

  • Broad-spectrum antibacterial activity
  • Rapid onset of action
  • Once-daily dosing in most cases
  • Effective against many penicillin-resistant strains
  • High tissue penetration
  • Long half-life for sustained action
  • Suitable for both adults and children

How It Works

Ceftriaxone interferes with bacterial cell wall synthesis by binding to penicillin-binding proteins. This action leads to the inhibition of cell wall formation, causing bacterial cell lysis and death. Its unique structure allows for extended plasma half-life and broad-spectrum activity.

Dosage

The typical adult dose is 1-2g once daily, or 500mg-1g twice daily, depending on the severity of the infection. For severe infections, doses up to 4g daily may be used. Always follow your doctor’s specific dosing instructions.

Side Effects

Common side effects may include diarrhea, nausea, vomiting, and pain at the injection site. Rarely, more serious side effects such as allergic reactions or blood disorders may occur. Consult your healthcare provider if you experience any unusual symptoms.

Warning

Avicef should only be used under medical supervision. Immediate medical attention is required if signs of an allergic reaction occur. Prolonged use may result in overgrowth of non-susceptible organisms.

Pregnancy and Breastfeeding

Avicef should be used during pregnancy only if clearly needed. It is excreted in human milk, so caution should be exercised when administered to nursing women. Consult your healthcare provider for guidance.

Interaction

  • May increase the anticoagulant effect of warfarin
  • Can interfere with some urine glucose tests
  • May increase the risk of kidney problems when used with loop diuretics
  • Potential interaction with calcium-containing solutions

Important Information

Complete the full course of treatment as prescribed, even if symptoms improve. Inform your doctor of any allergies, especially to penicillins or other beta-lactam antibiotics. Regular monitoring of liver and kidney function may be necessary during prolonged treatment. Store at room temperature, protected from light.

How to Use:
  1. Administration: Avicef Injection (Ceftriaxone) is administered via intramuscular (IM) or intravenous (IV) injection by a healthcare professional.
  2. Preparation: The injection should be reconstituted with a suitable diluent like sterile water, saline, or a specific diluent recommended by the manufacturer.
    • For IV injection, it is usually mixed with at least 10 mL of a suitable diluent and administered slowly over 2-4 minutes.
    • For IM injection, it can be mixed with 3.5 mL of a 1% lidocaine solution to reduce pain at the injection site and administered into a large muscle, such as the gluteus.
  3. Frequency: Typically given once or twice daily, depending on the severity of the infection and the doctor's prescription.
Dosage:
  • Adults: The typical dose ranges from 1-2 grams once a day or in divided doses every 12 hours. For severe infections, the dose may be increased to a maximum of 4 grams per day.
  • Children: The recommended dose is 50-75 mg/kg once daily or in two divided doses. The maximum dose should not exceed 2 grams per day.
  • Neonates (0-14 days old): 20-50 mg/kg once daily. For severe infections, up to 50 mg/kg may be used, but the daily dose should not exceed 50 mg/kg.
  • Elderly Patients: Dose adjustments may be required based on kidney function.
Note: Dosage and duration will vary based on the type of infection, patient age, kidney function, and response to treatment. Always follow the healthcare provider's instructions for specific dosing and administration guidelines. Precautions:
  • Check for allergies to cephalosporins or penicillins.
  • Monitor for potential side effects, such as allergic reactions, gastrointestinal discomfort, or signs of superinfection.
  • Avoid mixing ceftriaxone with calcium-containing solutions.
Always consult with a healthcare professional before starting or adjusting any treatment.

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