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Bristol Allopurinol 300mg Tablet x28

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Bristol Allopurinol 300mg is used to prevent and treat gout attacks. It also manages certain types of kidney stones and prevents uric acid buildup.

8,000.00

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SKU:ALL072

Bristol Allopurinol 300mg is a potent medication designed to treat gout and certain types of kidney stones. This prescription drug works by reducing the production of uric acid in the body, effectively managing symptoms and preventing future complications associated with high uric acid levels.

Uses

Bristol Allopurinol is primarily used to prevent and treat gout attacks. It’s also effective in managing certain types of kidney stones and may be prescribed for some patients undergoing chemotherapy to prevent uric acid buildup.

Benefits

  • Reduces frequency and severity of gout attacks
  • It helps prevent the formation of uric acid kidney stones
  • May lower the risk of kidney damage in gout patients
  • It can be used as a preventive measure in some cancer treatments
  • Provides long-term management of hyperuricemia
  • Once-daily dosing for most patients

How It Works

Allopurinol works by inhibiting the enzyme xanthine oxidase, which is responsible for producing uric acid in the body. Reducing uric acid production, it helps prevent the formation of urate crystals that cause gout and certain types of kidney stones.

Dosage

The typical starting dose is 100mg daily, which may be increased gradually to 300mg or higher if necessary. The 300mg tablet is often used for maintenance therapy. Always take Bristol Allopurinol exactly as prescribed by your healthcare provider.

Side Effects

Common side effects may include nausea, diarrhea, and drowsiness. Rarely, more serious side effects such as skin rashes or liver problems may occur. If you experience any unusual symptoms, contact your healthcare provider immediately.

Warning

Bristol Allopurinol 300mg can cause severe skin reactions in rare cases. Seek immediate medical attention if you develop a rash, especially if accompanied by fever or other symptoms. This medication may increase the risk of gout attacks when first started; your doctor may prescribe additional medication to prevent this.

Pregnancy and Breastfeeding

The safety of allopurinol during pregnancy and breastfeeding has not been fully established. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of this medication with your healthcare provider.

Interaction

  • May interact with certain antibiotics, increasing the risk of skin rashes
  • Can affect the metabolism of some medications used to treat leukemia and lymphoma
  • May increase the effect of blood thinners like warfarin
  • Can interact with diuretics, potentially affecting uric acid levels

Important Information

Take Bristol Allopurinol 300mg with food to reduce stomach upset. Drink plenty of fluids while taking this medication unless otherwise directed by your doctor. Regular blood tests may be necessary to monitor your uric acid levels and kidney function. Do not stop taking this medication without consulting your healthcare provider, as sudden discontinuation can trigger gout attacks. If you miss a dose, take it as soon as you remember, but skip it if it’s almost time for your next dose.

Category Dosage Instructions
Adults and Elderly Start with 100 mg once daily, increasing by 100 mg every week until the serum uric acid level is controlled. The usual maintenance dose is 200-300 mg daily (mild conditions) or 400-600 mg daily (moderate to severe conditions). The maximum dose should not exceed 800 mg per day.
Children (Under 15 years) 10-20 mg/kg body weight per day, divided into 3 doses, or as prescribed by a healthcare provider. Maximum dose of 400 mg daily.
Patients with Renal Impairment Dose adjustment may be necessary depending on kidney function. Typically, a reduced starting dose with close monitoring is advised. Consult with a healthcare provider.
Note: Allopurinol should be taken after meals with plenty of water to reduce the risk of gastrointestinal discomfort. Always follow the healthcare provider's instructions and adjust the dose based on uric acid levels and individual response to treatment.

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