BurnOut Cream (Silver Sulphadiazine)

BurnOut Cream is a medicated topical preparation containing Silver Sulphadiazine that provides antimicrobial protection for burn wounds. This specialized formulation helps prevent infection while creating an optimal environment for wound healing.

Uses

BurnOut Cream is primarily used for the prevention and treatment of infection in second and third-degree burns. It can also be applied to other wounds at risk of infection including skin grafts, donor sites, pressure ulcers, and large abrasions or lacerations where infection risk is high.

Benefits

• Broad-spectrum antimicrobial activity
• Effective against many bacteria and some fungi
• Forms protective barrier over wounds
• Reduces risk of burn wound infection
• Supports the wound healing process
• Easy application with minimal pain
• Prevents bacterial colonization
• Maintains moist wound environment

How It Works

BurnOut Cream releases silver ions that bind to bacterial cell walls and membranes, disrupting cellular processes. The sulphadiazine component interferes with bacterial folic acid synthesis. This dual-action mechanism prevents bacterial replication and kills existing bacteria while creating a protective barrier over the wound surface.

Duration of Action

Silver Sulphadiazine remains active on the wound surface for 8-12 hours after application. For optimal protection, reapplication is typically recommended 1-2 times daily, depending on wound characteristics and exudate levels.

Dosage

Warnings

Discontinue use and seek medical attention if increased pain, redness, swelling, or signs of allergic reaction develop. Long-term use on extensive burns may rarely lead to systemic absorption. Not recommended for use on facial burns near the eyes or on pregnant women near term.

Side Effects

Temporary burning sensation or pain may occur upon application. Skin discoloration (gray to black) is common where the cream is applied. Some patients may experience rash, itching, or transient leukopenia with extensive use. Rarely, prolonged use on large surface areas may affect kidney or liver function.

Pregnancy and Breastfeeding

Use BurnOut Cream with caution during pregnancy, especially in the third trimester. Silver Sulphadiazine may cause kernicterus in newborns if used near term. Consult a healthcare provider before use while breastfeeding as absorption and effects on nursing infants are not well established.

Interactions

• Enzymatic debridement agents (reduced effectiveness)
• Topical proteolytic enzymes (incompatible)
• Hydrogen peroxide (may reduce effectiveness)
• Other topical medications (potential antagonistic effects)
• Collagenase products (may be inactivated)
• Certain wound dressings (reduced efficacy)
• Topical corticosteroids (conflicting mechanisms)

Precautions

Clean the wound gently before application. Apply using sterile gloves or a sterile applicator. Do not cover with occlusive dressings unless directed by a healthcare provider. Reapply after wound cleansing or debridement. Monitor for signs of systemic absorption when used on large surface areas. Promptly discontinue use if sensitivity reactions occur.

Important Information

BurnOut Cream should be used under medical supervision, particularly for extensive or severe burns. Proper wound care and regular reassessment are essential components of burn management. Treatment with BurnOut Cream should continue until satisfactory healing has occurred or until the burn site is ready for grafting.