Camosunate Paediatric Powder 0-1 Years

Camosunate Paediatric Powder 0-1 Years is a combination antimalarial medication containing Artesunate 25mg and Amodiaquine 75mg per sachet. This artemisinin-based combination therapy (ACT) is specifically formulated for infants aged 0-11 months, providing a powerful and effective treatment for uncomplicated malaria caused by Plasmodium falciparum.

Uses

Camosunate Paediatric Powder is primarily used for:

• Treatment of uncomplicated malaria in infants aged 0-11 months
• First-line therapy for P. falciparum malaria in endemic regions
• Part of comprehensive malaria management programs

Benefits

• Highly effective against P. falciparum malaria
• Rapid reduction of parasite load
• Reduces risk of severe malaria complications
• Combination therapy helps prevent drug resistance
• Powder formulation allows for easy administration to infants
• Specifically dosed for the 0-11 month age group
• Part of WHO-recommended artemisinin-based combination therapies
• May reduce malaria transmission in endemic areas

How It Works

Artesunate rapidly reduces the parasite load in the blood, providing quick symptom relief. Amodiaquine acts as a longer-acting partner drug, eliminating remaining parasites and preventing recrudescence. This combination approach also helps to delay the development of drug resistance.

Dosage

The typical dosage is one sachet (Artesunate 25mg + Amodiaquine 75mg) once daily for 3 consecutive days. Always follow the specific instructions provided by your healthcare provider, as dosing may be adjusted based on the child’s exact weight.

Side Effects

Common side effects may include nausea, vomiting, loss of appetite, and dizziness. These are usually mild and resolve on their own. Serious side effects are rare but can include severe allergic reactions or blood disorders. Consult a healthcare provider immediately if any severe or persistent side effects occur.

Warning

Do not use in infants with known hypersensitivity to artesunate or amodiaquine. Use with caution in patients with liver or heart problems. Complete the full 3-day course of treatment even if symptoms improve quickly. Seek medical attention if fever persists or returns after treatment.

Pregnancy and Breastfeeding

While this formulation is specifically for infants, it’s important to note that artemisinin-based combinations are generally considered safe during pregnancy and breastfeeding. However, always consult a healthcare provider for specific advice in these situations.

Interaction

• May interact with other medications that affect heart rhythm
• Potential interaction with drugs metabolized by the liver
• May enhance the effects of drugs that cause QT prolongation
• Possible interaction with antiretroviral medications
• Could affect the efficacy of certain vaccines if administered concurrently

Important Information

Camosunate Paediatric Powder should only be used after a confirmed diagnosis of malaria. Proper weight-based dosing is crucial for effective treatment. Store in a cool, dry place and protect from light. Reconstitute the powder with clean water immediately before administration. If the child vomits within 30 minutes of taking a dose, repeat the dose. Continue protective measures against mosquito bites to prevent reinfection.