Co-Diovan 160mg/12.5mg combines valsartan (160mg) and hydrochlorothiazide (12.5mg) in a single tablet. This dual-action antihypertensive medication effectively manages high blood pressure through complementary mechanisms, offering comprehensive cardiovascular protection.
Uses
Co-Diovan is primarily prescribed for treating essential hypertension in adults where blood pressure is not adequately controlled by monotherapy. It’s particularly effective for patients requiring combination therapy for optimal blood pressure management.
Benefits
- Provides dual mechanism blood pressure control
- Offers effective 24-hour blood pressure management
- Reduces risk of cardiovascular complications
- Improves overall cardiovascular health
- Shows excellent tolerability profile
- Convenient once-daily dosing
- Demonstrates consistent blood pressure reduction
- Supports better patient compliance
How It Works
The medication works through two complementary mechanisms: valsartan blocks angiotensin II receptors, reducing blood vessel constriction, while hydrochlorothiazide increases water and sodium excretion, lowering blood volume and pressure.
Duration of Action
Blood pressure reduction typically begins within 2 weeks, with maximum effects achieved within 4-6 weeks of consistent use. The 24-hour coverage ensures sustained blood pressure control with once-daily dosing.
Dosage
Patient Category | Daily Dose | Maximum Dose |
---|---|---|
Standard Adult | One tablet once daily | Two tablets once daily |
Elderly | One tablet once daily | As directed by physician |
Side Effects
Common effects may include mild dizziness, fatigue, and electrolyte changes. More serious side effects like severe dizziness, fainting, or significant electrolyte imbalances require immediate medical attention.
Warning
Seek immediate medical care if experiencing severe dizziness, fainting, rapid or irregular heartbeat, severe dehydration, or unusual muscle weakness. Monitor blood pressure regularly during treatment.
Pregnancy and Breastfeeding
Co-Diovan 160mg/12.5mg is contraindicated during pregnancy as it can cause fetal harm. Women who become pregnant should discontinue use immediately. Not recommended during breastfeeding due to potential risks to the infant.
Interactions
- May interact with other blood pressure medications
- Caution with NSAIDs and pain relievers
- Potential interactions with potassium supplements
- May affect lithium levels in the body
Precautions
Regular monitoring of blood pressure, kidney function, and electrolytes is essential. Patients with kidney disease, liver problems, or diabetes require close medical supervision. Avoid excessive alcohol consumption during treatment.
Important Information
Take Co-Diovan 160mg/12.5mg consistently at the same time each day, preferably in the morning. Regular blood pressure monitoring helps ensure optimal dosing. Report any unusual symptoms to your healthcare provider promptly. Lifestyle modifications, including diet and exercise, enhance treatment effectiveness.
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