Dithrotec Tablet (Diclofenac+Misoprostol) x100

Dithrotec Tablet is a combination prescription medication containing Diclofenac (a nonsteroidal anti-inflammatory drug) and Misoprostol (a prostaglandin that protects the stomach). This unique combination provides effective pain relief while protecting against gastrointestinal complications.

Uses

Dithrotec Tablet is specifically prescribed for treating chronic pain and inflammation associated with osteoarthritis and rheumatoid arthritis, particularly in patients at high risk of developing gastric ulcers. The medication is designed for adult patients requiring long-term NSAID treatment.

Benefits

• Provides effective pain relief
• Reduces inflammation in joints
• Protects against gastric ulcers
• Improves joint mobility
• Reduces morning stiffness
• Offers gastric protection during NSAID therapy
• Decreases risk of GI complications
• Provides 24-hour symptom control
• Enhances quality of life
• Cost-effective compared to separate medications

How It Works

Diclofenac works by reducing inflammation, pain, and fever by blocking COX enzymes and reducing prostaglandin production. Misoprostol protects the stomach lining by replacing natural prostaglandins that are reduced by NSAIDs, thereby preventing ulcer formation.

Duration of Action

Pain relief begins within 30-60 minutes after taking Dithrotec. Anti-inflammatory effects are typically noticed within 1-2 days of regular use. Gastric protection begins immediately and maintains effectiveness with consistent use.

Dosage

Standard dosage: One tablet 2-3 times daily with meals Maximum daily dose: 4 tablets per day Take with full glass of water Must be taken with food Duration based on medical condition and response

Side Effects

Initial diarrhea and abdominal pain are common but usually temporary. Other side effects may include nausea, headache, dizziness, and flatulence. Most side effects diminish with continued use.

Warning

Not for use during pregnancy. May increase risk of cardiovascular events. Avoid alcohol consumption. Monitor blood pressure regularly. Discontinue if signs of liver or kidney problems occur. Not suitable for patients with aspirin-sensitive asthma.

Pregnancy and Breastfeeding

Strictly contraindicated during pregnancy due to risk of miscarriage and birth defects. Women of childbearing age must use effective contraception during treatment. Not recommended during breastfeeding.

Interactions

• May interact with blood thinners
• Can interact with other NSAIDs
• Potential interaction with antihypertensive medications
• May affect lithium levels
• Can interact with diuretics
• Possible interaction with methotrexate
• May interact with aspirin therapy

Important Information

Take exactly as prescribed. Must be swallowed whole with food. Avoid lying down for 30 minutes after taking. Regular monitoring of kidney and liver function required. Store below 25°C in a dry place. Women of childbearing age must have negative pregnancy test before starting treatment.