Dostril 5mg (Lisinopril) is a potent angiotensin-converting enzyme (ACE) inhibitor designed to treat hypertension, heart failure, and post-heart attack recovery. This prescription medication effectively manages blood pressure by relaxing blood vessels, improving blood flow and reducing strain on the heart.
Uses
Dostril is primarily prescribed for treating high blood pressure (hypertension), managing chronic heart failure, and improving survival after heart attacks. It’s also effective in treating diabetic kidney disease and can help protect the kidneys from further damage in patients with diabetes and high blood pressure.
Benefits
- Effectively lowers high blood pressure
- Reduces risk of heart attack and stroke
- Improves survival rates after heart attack
- Protects kidney function in diabetic patients
- Helps manage symptoms of heart failure
- Reduces workload on the heart
- Improves overall cardiovascular health
- Enhances quality of life for heart patients
How It Works
Lisinopril blocks the production of angiotensin II, a hormone that narrows blood vessels. By inhibiting this hormone, Dostril helps blood vessels relax and widen, lowering blood pressure and reducing the workload on the heart. This mechanism also improves blood flow throughout the body.
Duration of Action
The blood pressure-lowering effect begins within 1 hour of taking Dostril, with peak effects occurring at 6 hours. The full therapeutic effect is usually achieved after 2-4 weeks of regular use. Each dose typically remains effective for 24 hours.
Dosage
Condition | Initial Dose | Maintenance/Maximum Dose |
---|---|---|
Hypertension | 5-10mg once daily | 20-40mg once daily (up to 80mg) |
Heart Failure | 2.5mg once daily | 5-20mg once daily (up to 40mg) |
Post Heart Attack | 5mg within 24 hours | 10mg daily |
Side Effects
Common side effects include dizziness, headache, dry cough, and mild fatigue. These typically improve as your body adjusts to the medication. More serious side effects may include swelling of face/lips/tongue, difficulty breathing, or severe dizziness.
Warning
Discontinue Dostril 5mg Tablet and seek immediate medical attention if you experience swelling of the face, throat, or tongue, as this may indicate a serious allergic reaction. Regular monitoring of blood pressure and kidney function is essential.
Pregnancy and Breastfeeding
Dostril 5mg Tablet is contraindicated during pregnancy as it can cause serious harm to the developing fetus. Women who are breastfeeding should consult their healthcare provider as the drug can pass into breast milk.
Interactions
- Potassium supplements or salt substitutes
- NSAIDs (like ibuprofen)
- Diuretics (water pills)
- Lithium
- Injectable gold preparations
- Aliskiren-containing medicines
- Other blood pressure medications
Precautions
Monitor blood pressure regularly. Take the first dose at bedtime to minimize dizziness. Stay well-hydrated but avoid excessive alcohol. Regular blood tests may be required to monitor kidney function and potassium levels.
Important Information
Take Dostril 5mg Tablet at the same time each day. Don’t stop taking it suddenly without consulting your doctor. Keep all follow-up appointments for monitoring. If you miss a dose, take it as soon as you remember, unless it’s almost time for your next dose.
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