Duphaston 10mg Tablet (Dydrogesterone) x20

Duphaston 10mg Tablet contains dydrogesterone, a synthetic progestogen that mimics the effects of naturally occurring progesterone. This medication is widely used in various gynecological conditions and plays a crucial role in hormone replacement therapy and pregnancy support.

Uses

Duphaston is prescribed for multiple gynecological conditions, including:

• Treatment of menstrual disorders such as dysmenorrhea and irregular cycles
• Management of endometriosis
• Treatment of threatened or recurrent miscarriage
• Hormone replacement therapy in combination with estrogen
• Infertility due to luteal insufficiency
• Premenstrual syndrome (PMS)
• Dysfunctional uterine bleeding

Benefits

• Helps regulate menstrual cycles
• Reduces pain and discomfort associated with endometriosis
• Supports early pregnancy and reduces risk of miscarriage in certain cases
• Balances hormones during menopause when used in hormone replacement therapy
• Aids in treating infertility related to luteal phase defects
• Alleviates symptoms of premenstrual syndrome

How it works

Dydrogesterone, the active ingredient in Duphaston, acts similarly to natural progesterone. It helps prepare the uterus for pregnancy, maintains pregnancy, and regulates the menstrual cycle. In hormone replacement therapy, it protects the endometrium from excessive estrogen stimulation.

Dosage

The dosage of Duphaston varies depending on the condition being treated. Typical dosages range from 10mg to 40mg daily, often divided into two doses. Always follow your doctor’s prescription and instructions carefully.

Side Effects

Common side effects may include:

• Headache
• Nausea
• Breast tenderness
• Menstrual spotting
• Dizziness Less common side effects can include allergic reactions, mood changes, and abdominal pain. If you experience severe side effects, contact your healthcare provider immediately.

Warning

Duphaston should not be used in cases of known or suspected breast or genital organ cancers, liver disease, or during pregnancy (unless specifically prescribed for pregnancy support). It may interact with certain medications, so inform your doctor about all medicines you’re taking.

Drug Interactions

Duphaston may interact with:

• Enzyme inducers (e.g., rifampicin, carbamazepine) which may reduce its effectiveness
• Ketoconazole and other potent CYP3A4 inhibitors, potentially increase dydrogesterone levels
• Herbal products containing St. John’s Wort, which may reduce Duphaston’s effectiveness

Always consult your healthcare provider about potential drug interactions.

Important Information

Duphaston should be taken as prescribed by your doctor. It’s not a contraceptive and doesn’t protect against sexually transmitted diseases. Regular check-ups are important while using this medication, especially if used for hormone replacement therapy. If you’re planning to become pregnant, discuss the use of Duphaston with your healthcare provider.