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Epilim 200mg Tablet (Sodium valproate) x100

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Epilim 200mg is anticonvulsant medication valproic acid. It is used to treat seizure disorders, including epilepsy, bipolar disorder, and migraine headaches.

75,000.00

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SKU:EPP446

Epilim 200mg Tablet is a specialized anticonvulsant and mood stabilizer containing modified-release sodium valproate. It provides sustained therapeutic effects for patients with epilepsy and bipolar disorder, helping maintain consistent neurotransmitter levels for improved symptom control.

Uses

Epilim 200mg Tablet is primarily used for prevention of recurrent general and partial epileptic seizures and long-term management of bipolar disorder, including mood stabilization, mania/psychosis control, and impulsivity regulation.

Benefits

  • Reduces frequency and intensity of epileptic seizures
  • Stabilizes mood in bipolar disorder patients
  • Minimizes extreme emotional and behavioral fluctuations
  • Improves overall quality of life for patients
  • Enables more normal daily functioning
  • Provides sustained release for consistent therapeutic levels
  • Helps prevent manic episodes in bipolar disorder
  • Reduces need for multiple daily doses

How It Works

Epilim’s active ingredient, sodium valproate, enhances GABA receptor functioning and blocks voltage-gated sodium channels. This mechanism inhibits uncontrolled neuronal firing, suppressing seizures and regulating neurotransmitters to stabilize mood.

Duration of Action

The modified-release formulation provides therapeutic effects for approximately 12-24 hours per dose. Steady-state plasma concentrations are typically achieved within 3-4 days of consistent dosing.

Dosage

Patient Type Recommended Dosage Frequency
Initial dose 200mg Twice daily
Maintenance 400-1000mg Divided doses
Maximum 2000mg total daily Divided doses

Warnings

Report any signs of depression, suicidal thoughts, or jaundice immediately. Gradual dose reduction is essential when stopping after long-term usage. Regular blood cell count monitoring is required. Do not abruptly discontinue without medical supervision.

Side Effects

Common side effects may include nausea, drowsiness, and weight gain. Serious side effects, though rare, can include liver problems or pancreatitis. Consult your doctor if you experience any concerning symptoms.

Pregnancy and Breastfeeding

Epilim can cause serious birth defects. Avoid pregnancy during treatment. If pregnant or planning pregnancy, consult your doctor immediately. Breastfeeding while taking Epilim is not recommended without medical advice.

Interactions

  • May interact with other anticonvulsants
  • Potential interactions with antidepressants
  • Some antibiotics may affect levels
  • Alcohol consumption should be avoided
  • Blood thinners may have altered effectiveness
  • Certain sedatives may increase drowsiness
  • Some antipsychotic medications require dose adjustment

Precautions

Take Epilim 200mg Tablet with food to minimize gastrointestinal upset. Store at room temperature away from moisture and heat. Do not crush, chew, or break the modified-release tablets as this can alter the drug’s release pattern and potentially cause side effects.

Important Information

Seek urgent medical care if signs of serious allergic reactions appear. Ensure compliance through regular physician follow-ups. This medication requires careful monitoring and should only be used under close medical supervision. Regular liver function tests may be necessary during long-term treatment.

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Epilim 200mg
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Category Dosage Instructions
Adults (Epilepsy) Start with 600 mg daily (in divided doses). Increase by 200 mg every 3 days until seizures are controlled. Maintenance dose: typically 1000-2000 mg daily. Maximum: 2500 mg daily.
Adults (Bipolar Disorder) Initial dose: 600-1000 mg daily (in divided doses). Maintenance dose: Adjust based on response, typically 1000-2000 mg daily.
Children (Epilepsy) 20 kg or more Start with 300 mg daily (in divided doses). Adjust based on response, usually 20-30 mg/kg/day. Maximum: 35 mg/kg/day.
Children (Epilepsy) under 20 kg Start with 20 mg/kg/day (in divided doses). Increase gradually. Maximum: 40 mg/kg/day.
Elderly Patients Start with a lower dose and adjust based on clinical response and tolerability. Monitor closely for side effects.
Patients with Liver Impairment Use with caution; dose adjustments may be necessary. Regular liver function tests are recommended.
Administration Instructions Take orally with food to minimize gastrointestinal discomfort. Divide the total daily dose into two or more smaller doses.
Missed Dose If a dose is missed, take it as soon as remembered unless it is almost time for the next dose. Do not double the dose to make up for a missed one.

Important Notes:

  • Indications: Used to treat various types of seizures (epilepsy) and bipolar disorder, and for migraine prophylaxis.
  • Side Effects: Common side effects may include nausea, dizziness, drowsiness, weight gain, hair loss, tremors, or gastrointestinal discomfort. Severe side effects may include liver damage, pancreatitis, or severe allergic reactions. Seek medical advice if severe symptoms occur.
  • Pregnancy and Breastfeeding: Not recommended during pregnancy due to the risk of birth defects. Consult a healthcare provider before use if you are pregnant or breastfeeding.
  • Interactions: May interact with other antiepileptic drugs, antidepressants, anticoagulants, and certain antibiotics. Inform your healthcare provider of all medications you are taking.
  • Monitoring: Regular monitoring of liver function, complete blood count (CBC), and serum drug levels is recommended.
  • Special Precautions: Use caution in patients with liver disease, pancreatitis, or urea cycle disorders. Avoid abrupt discontinuation of the medication to prevent withdrawal seizures.
  • Storage Instructions: Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.

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