Ex Fluconazole 150mg Tablet is a potent antifungal medication belonging to the triazole class. It’s primarily used to treat a variety of fungal infections, including vaginal yeast infections, oral thrush, and certain systemic fungal infections.
Uses
Ex Fluconazole 150mg is primarily used for:
- Treatment of vaginal candidiasis (yeast infections)
- Management of oropharyngeal and esophageal candidiasis
- Treatment of certain systemic fungal infections
- Prevention of fungal infections in immunocompromised patients
Benefits
- Effective against a wide range of fungal infections
- Single-dose treatment option for vaginal yeast infections
- Can be used for both treatment and prophylaxis
- Generally well-tolerated with fewer side effects than some alternatives
- Oral formulation allows for convenient administration
- Long half-life enables once-daily dosing for most indications
How It Works
Fluconazole inhibits the fungal enzyme 14α-demethylase, which is crucial for ergosterol production in fungal cell membranes. This leads to the accumulation of toxic sterols, disrupting membrane structure and function, ultimately causing fungal cell death.
Dosage
For vaginal candidiasis, the typical dose is a single 150mg tablet taken orally. For other infections, dosage and duration may vary. Always follow your healthcare provider’s specific dosing instructions.
Side Effects
Common side effects may include headache, nausea, abdominal pain, and diarrhea. Less common effects can include skin rash and altered taste. Rare but serious side effects may include liver problems or severe skin reactions. Consult your healthcare provider if you experience severe or persistent side effects.
Warning
Not recommended during pregnancy unless the potential benefit outweighs the risk. Use caution in patients with liver disease. May cause QT prolongation in some individuals. Not suitable for treating fungal meningitis or certain systemic fungal infections.
Interactions
May interact with numerous medications including warfarin, oral hypoglycemics, phenytoin, and cyclosporine. Can increase the effect of benzodiazepines. Always inform your healthcare provider about all medications you’re taking.
Important Information
Take with or without food. For vaginal yeast infections, symptoms should improve within a few days, but it may take up to a week for complete resolution. If symptoms persist or worsen, consult your healthcare provider. Do not use for self-treatment of systemic fungal infections. If you have recurrent yeast infections (4 or more in a year), seek medical advice as this may indicate an underlying condition.
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