Gastroloc Injection contains 40mg of omeprazole, a potent proton pump inhibitor (PPI) designed for intravenous administration. This formulation provides rapid and effective acid suppression for patients unable to take oral medications or requiring immediate acid reduction.
Uses
Gastroloc Injection is primarily indicated for:
- Treatment of acute peptic ulcer disease
- Management of severe gastroesophageal reflux disease (GERD)
- Prevention of stress-related mucosal damage in critically ill patients
- Treatment of Zollinger-Ellison syndrome
- Management of bleeding peptic ulcers
- Facilitating healing in erosive esophagitis
Benefits
- Provides rapid acid suppression
- Enables immediate treatment for patients unable to take oral medications
- Offers consistent and predictable acid reduction
- Supports healing of gastrointestinal mucosal damage
- Prevents further complications from acid-related disorders
- Demonstrates high efficacy in critical care settings
- Reduces risk of gastrointestinal bleeding
How It Works
Omeprazole works by irreversibly blocking the proton pump (H+/K+ ATPase) in gastric parietal cells, dramatically reducing gastric acid production. This mechanism provides profound and long-lasting acid suppression, facilitating healing of acid-related conditions.
Duration of Action
Peak acid suppression occurs within 1-2 hours of administration. Therapeutic effects can last 24-72 hours, depending on individual patient factors and underlying condition.
Dosage
Condition | Typical Dosage | Administration | Frequency |
---|---|---|---|
Peptic Ulcer | 40mg | IV infusion | Once daily |
Severe GERD | 40mg | IV infusion | Once daily |
Zollinger-Ellison | Individualized | IV infusion | As directed |
Stress Ulcer Prophylaxis | 40mg | IV infusion | Once daily |
Side Effects
Common effects may include:
- Headache
- Nausea
- Diarrhea
- Dizziness
- Potential electrolyte imbalances
Warning
Avoid prolonged use without medical supervision. Monitor for potential vitamin B12 deficiency with extended use. Not recommended for patients with severe hepatic impairment.
Pregnancy and Breastfeeding
Limited data available. Consult healthcare provider to assess risk-benefit ratio during pregnancy and breastfeeding.
Interactions
- May interact with anticoagulants
- Could affect absorption of certain medications
- Potential interactions with antifungal drugs
- May influence metabolism of certain medications
Precaution
Administer under medical supervision. Monitor liver function during prolonged use. Adjust dosage for patients with hepatic impairment.
Important Information
Store at controlled room temperature. Protect from light and moisture. Reconstitute only with recommended diluents. Use immediately after preparation. Do not store reconstituted solution. Discard unused portion. Monitor for signs of hypersensitivity. Inform healthcare provider of all concurrent medications.
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