Glucophage XR 1000mg is an extended-release formulation of metformin, a medication used primarily in the treatment of Type 2 diabetes. This higher-dose, once-daily tablet is designed to provide prolonged blood sugar control throughout the day.
Uses
Glucophage XR 1000mg is used for the treatment of Type 2 diabetes in adults, particularly when diet and exercise alone have not been sufficient to control blood glucose levels. It may be prescribed as a first-line treatment or in combination with other diabetes medications. In some cases, it’s also used off-label for conditions related to insulin resistance, such as polycystic ovary syndrome (PCOS).
Benefits
- Provides extended blood glucose control over 24 hours
- Improves insulin sensitivity
- Reduces hepatic glucose production
- May aid in weight management
- Lowers the risk of diabetes-related complications
- Convenient once-daily dosing
- May have cardiovascular benefits
How It Works
Glucophage XR 1000mg works by decreasing the amount of glucose produced by the liver and improving the body’s sensitivity to insulin. It also reduces glucose absorption in the intestines. The extended-release formulation allows for a more gradual and prolonged release of the medication, providing consistent blood sugar control throughout the day.
Dosage
The typical starting dose is 500mg or 1000mg once daily with the evening meal. Dosage may be gradually increased based on effectiveness and tolerability, up to a maximum of 2000mg once daily. Always follow your healthcare provider’s instructions regarding dosage.
Side Effects
Common side effects may include nausea, diarrhea, stomach upset, and changes in taste. These often improve over time. Serious side effects are rare but can include lactic acidosis, especially in people with kidney problems.
Warning
Glucophage XR 1000mg may cause a rare but serious condition called lactic acidosis. Seek immediate medical attention if you experience symptoms such as unusual muscle pain, difficulty breathing, stomach discomfort, or extreme tiredness. This risk is higher in people with kidney problems, liver disease, or conditions causing low oxygen levels.
Pregnancy and Breastfeeding
Consult your healthcare provider before using Glucophage XR 1000mg if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this medication during pregnancy and lactation needs to be carefully evaluated.
Interaction
- May interact with certain contrast dyes used in medical imaging
- Can interact with other diabetes medications, potentially causing low blood sugar
- Alcohol may increase the risk of lactic acidosis
- Some medications may affect the kidneys, increasing the risk of side effects
Important Information
Regular monitoring of blood glucose levels is essential while taking Glucophage XR 1000mg. Maintain a healthy diet and exercise routine as recommended by your healthcare provider. The tablet should be swallowed whole and not crushed or chewed. Take the medication with food to minimize gastrointestinal side effects. If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. Never take a double dose to make up for a missed one.
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Customer questions & answers
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I started using this medication yesterday and experienced headaches
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Q I started using this medication yesterday and experienced headaches answer nowAsked by Joyce on August 28, 2024 6:09 amA
Hi Joyce,
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Headaches can be a common side effect when starting Glucophage XR (metformin extended-release) 1000 mg, especially as your body adjusts to the medication. If the headaches are mild and manageable, they may improve over time. However, if they are severe, persistent, or accompanied by other symptoms, it's important to consult your healthcare provider. They may need to adjust your dosage or explore alternative treatment options. Always follow your doctor’s advice and report any new or worsening symptoms.
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