Humulin R is a short-acting regular human insulin used for blood glucose management. This clear, colorless solution contains 100 units/mL of biosynthetic human insulin, providing rapid blood sugar control. It’s designed to closely mimic the body’s natural insulin response to meals.
Uses
Humulin R is prescribed for managing blood glucose levels in patients with type 1 and type 2 diabetes mellitus. It’s particularly effective for controlling post-meal blood sugar spikes and can be used in insulin pumps. The medication is also utilized in hospital settings for managing diabetic ketoacidosis.
Benefits
- Provides rapid blood sugar control
- Flexible dosing with meals
- Compatible with insulin pumps
- Helps prevent diabetic complications
- Suitable for emergency glucose management
- Can be mixed with longer-acting insulins
- Cost-effective diabetes treatment option
- Predictable onset and duration
How It Works
Humulin R works by stimulating cells to absorb glucose from the bloodstream and inhibiting glucose production by the liver. This synthetic insulin mimics the natural pancreatic insulin release, helping to metabolize carbohydrates, proteins, and fats effectively.
Dosage
| Usage Type | Timing | Recommended Administration |
|---|---|---|
| Meal Coverage | 30 mins before meals | Individual dose based on glucose levels |
| Insulin Pump | As needed | According to pump protocols |
| Hospital Use | As required | Per sliding scale or protocol |
Duration of Action
Onset begins within 30 minutes of injection, with peak effect occurring between 2-3 hours. The duration of action typically lasts 3-6 hours. Effects may vary based on individual factors such as injection site, exercise, and metabolism.
Side Effects
Common side effects include hypoglycemia, injection site reactions, and weight gain. Serious side effects, though rare, may include severe low blood sugar, allergic reactions, or electrolyte imbalances. Monitor blood glucose regularly and report concerning symptoms.
Warning
Risk of severe hypoglycemia if dosing is incorrect or meals are delayed. Never share insulin devices. Monitor blood sugar closely when starting or adjusting doses. Seek immediate medical attention for severe hypoglycemia or allergic reactions.
Pregnancy and Breastfeeding
Humulin R can be safely used during pregnancy and breastfeeding under medical supervision. Insulin needs often change during pregnancy, requiring frequent monitoring and dose adjustments.
Interactions
- Beta-blockers may mask hypoglycemic symptoms
- Oral diabetes medications may enhance insulin effects
- Corticosteroids can increase insulin requirements
- Thyroid medications may affect glucose control
- Alcohol may intensify hypoglycemic effects
Precautions
Check blood glucose regularly. Rotate injection sites to prevent tissue damage. Always keep a quick sugar source available. Adjust doses for changes in diet, exercise, or illness. Store unopened vials in refrigerator and in-use vials at room temperature.
Important Information
Inspect Humulin R before each use – it should be clear and colorless. Avoid freezing or extreme heat exposure. Carry medical identification indicating diabetes and insulin use. Maintain consistent meal timing and daily routines for optimal glucose control. Regular medical follow-up is essential for dose adjustments and monitoring long-term management with Humulin R.
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