INS Letrozole 2.5mg Tablet is a potent non-steroidal aromatase inhibitor used primarily in the treatment of hormone-receptor-positive breast cancer in postmenopausal women. This prescription medication works by reducing estrogen production in the body, which can slow or stop the growth of certain types of breast tumors.
Uses
INS Letrozole 2.5mg Tablet is used to treat:
- Early-stage hormone-receptor-positive breast cancer in postmenopausal women
- Advanced or metastatic breast cancer as first-line treatment in postmenopausal women
- Extended adjuvant treatment of early breast cancer in postmenopausal women
- Advanced breast cancer in postmenopausal women with disease progression after tamoxifen therapy
Benefits
- Effectively reduces estrogen production in postmenopausal women
- May slow or stop the growth of hormone-sensitive breast tumors
- Can be used as initial therapy or after other treatments like tamoxifen
- May improve disease-free survival in early-stage breast cancer
- Once-daily oral dosing for convenient administration
- Well-established efficacy and safety profile
How It Works
Letrozole inhibits the aromatase enzyme, which is responsible for converting androgens to estrogens in postmenopausal women. By reducing estrogen levels, it deprives hormone-sensitive breast cancer cells of the estrogen they need to grow and multiply.
Dosage
The typical recommended dose is one 2.5mg tablet taken once daily, with or without food. Treatment duration varies based on the specific condition being treated and individual response. Always follow your oncologist’s prescription and instructions.
Side Effects
Common side effects may include hot flashes, joint pain, fatigue, headache, and mild nausea. More serious side effects, though less common, can include osteoporosis, increased cholesterol levels, and cardiovascular events. Report any persistent or severe side effects to your healthcare provider.
Warning
INS Letrozole is not for use in premenopausal women or men. It may harm an unborn baby, so effective contraception is necessary during treatment. Regular bone density scans may be recommended due to increased risk of osteoporosis.
Interaction
- Tamoxifen (may reduce letrozole effectiveness)
- Strong CYP3A4 inhibitors (may increase letrozole levels)
- Estrogen-containing products (may interfere with treatment effectiveness)
Important Information
INS Letrozole is a prescription medication that should only be used under the supervision of an oncologist. Regular follow-ups and blood tests are necessary to monitor treatment efficacy and side effects. Calcium and vitamin D supplements may be recommended to support bone health. Inform your doctor of any other medications or supplements you’re taking. If you experience severe joint pain, chest pain, or signs of a blood clot, seek immediate medical attention. Do not stop taking this medication without consulting your oncologist.
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