Kriscet-400 Cimetidine Caplets x20

Kriscet-400 Cimetidine is a medication containing the active ingredient cimetidine 400mg. It belongs to a class of drugs called histamine-2 receptor antagonists or H2 blockers, which reduce the production of stomach acid.

Uses

The main uses of Kriscet-400 include:

• Treatment of acid reflux and gastroesophageal reflux disease (GERD)
• Healing and prevention of gastric and duodenal ulcers
• Relief of active duodenal ulcers and associated pain
• Prevention of upper gastrointestinal bleeding in critically ill patients
• Management of pathological hypersecretory conditions like Zollinger-Ellison syndrome

Benefits

Key benefits of taking Kriscet-400 include:

• Effectively reduces the amount of acid produced by the stomach
• Promotes healing of existing ulcers and prevents new ones from forming
• Relief from acid reflux, heartburn, and associated discomfort
• Helps prevent stress-related upper GI bleeding in high-risk patients
• Improves overall symptoms and quality of life for those with acid disorders

Mechanism of Action

Cimetidine is an H2 receptor antagonist that reversibly binds to and blocks histamine H2 receptors in the stomach lining. This inhibits the action of histamine on the parietal cells, reducing gastric acid secretion.

Dosage

The typical dosage for duodenal ulcers is 800mg daily in divided doses or 400mg twice daily at bedtime and in the morning. For other conditions, 400mg twice daily or 800mg at bedtime. Adjust dosage in renal impairment cases.

Side Effects

Common side effects include headache, diarrhea, constipation, dizziness, rash, and muscle pain. Serious but rare effects like confusion, gynecomastia, agranulocytosis, or liver problems may occur.

Warnings

Avoid use if allergic to cimetidine. Use with caution in kidney disease, lung disease, or G6PD deficiency. Avoid alcohol and high-protein intake. Discontinue if pregnancy occurs.

Important Information

Take Kriscet-400 as prescribed, with food or antacids if needed. Do not take concurrently with other acid-reducing medications. Report worsening symptoms or new side effects promptly to your doctor.