Lokmal Suspension is an oral, fruit-flavored antimalarial medication containing artemether and lumefantrine. It is specifically formulated as a suspension for easy administration to infants and children with body weight less than 35 kg.
Uses
 Lokmal Suspension is used to treat acute, uncomplicated malaria caused by the Plasmodium falciparum parasite in infants and young children.
Benefits
The artemether-lumefantrine combination provides rapid parasite clearance, effectiveness against resistant strains, reduced risk of resistance development, and improved palatability for pediatric use.
Mechanism of Action
Artemether rapidly reduces the parasite load, while lumefantrine disrupts the parasite’s ability to replicate in red blood cells, working synergistically to clear the infection.
Dosage
General Dosage Guidelines for Lokmal Suspension
Dosage Based on Body Weight
| Weight Range | Day 1 (Initial Dose + 8 hours later) | Day 2 (Every 12 hours) | Day 3 (Every 12 hours) |
|---|---|---|---|
| 5 kg to <15 kg | 1 dose (morning) + 1 dose (8 hours later) | 1 dose (morning) + 1 dose (evening) | 1 dose (morning) + 1 dose (evening) |
| 15 kg to <25 kg | 2 doses (morning) + 2 doses (8 hours later) | 2 doses (morning) + 2 doses (evening) | 2 doses (morning) + 2 doses (evening) |
| 25 kg to <35 kg | 3 doses (morning) + 3 doses (8 hours later) | 3 doses (morning) + 3 doses (evening) | 3 doses (morning) + 3 doses (evening) |
| 35 kg and above | 4 doses (morning) + 4 doses (8 hours later) | 4 doses (morning) + 4 doses (evening) | 4 doses (morning) + 4 doses (evening) |
The dosage is carefully calculated based on the child’s body weight and administered over a three-day course, with doses given at specific intervals as prescribed.
Side Effects
Common side effects may include fever, headache, diarrhea, vomiting, and loss of appetite. Seek prompt medical attention if severe or persistent side effects occur.
Warning
Not intended for severe malaria cases requiring hospitalization. Use caution in liver or kidney disease. Follow dosage instructions carefully to ensure proper treatment.
Important Information
Shake the suspension well before each use to ensure proper mixing. Complete the full three-day course as directed, even if symptoms improve. Store at room temperature, and discard any unused portion after completing the treatment course.
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