Malanter Ds Tablets is an antimalarial medication that contains two active ingredients: artemether (80mg) and lumefantrine (480mg). This combination therapy is used to treat uncomplicated malaria caused by the Plasmodium falciparum parasite, which is known to be the most severe and life-threatening form of malaria.
Uses
Malanter Ds Tablets are specifically used for the treatment of acute, uncomplicated malaria infections caused by Plasmodium falciparum, a strain of the malaria parasite that is resistant to many other antimalarial drugs. This medication is typically prescribed for adults and children weighing over 35 kg (77 lbs).
Benefits
The combination of artemether and lumefantrine in Malanter Ds Tablets provides several benefits in the treatment of malaria:
- Rapid clearance of the malaria parasite from the bloodstream, reducing the risk of severe complications and improving recovery time.
- Effective against drug-resistant strains of Plasmodium falciparum, making it a valuable treatment option in areas where resistance is common.
- Combination therapy helps to reduce the risk of developing resistance to either of the active ingredients when used alone.
- Improved tolerability and reduced side effects compared to some other antimalarial medications.
Mechanism of Action
Artemether and lumefantrine work together to disrupt the life cycle of the Plasmodium falciparum parasite in different ways:
- Artemether is a potent and rapidly acting antimalarial compound that targets the asexual stages of the parasite’s life cycle, rapidly reducing the parasite load in the bloodstream.
- Lumefantrine is a longer-acting antimalarial that acts on the parasite’s membrane, disrupting its ability to replicate and spread within the host’s red blood cells.
The combination of these two active ingredients provides a synergistic effect, effectively clearing the malaria infection and reducing the risk of resistance development.
Dosage
Malanter Dosage
A three-day course, with the initial dose followed by subsequent doses at 8-hour intervals, as prescribed.
Dosage Guidelines for Malanter DS
Adults and Children (weighing at least 35 kg)
| Day | Dosage | Frequency |
|---|---|---|
| Day 1 | 1 tablet | At the time of diagnosis |
| 1 tablet | 8 hours after the first dose | |
| Day 2 | 1 tablet | 12 hours after the second dose (morning) |
| 1 tablet | 12 hours after the third dose (evening) | |
| Day 3 | 1 tablet | 12 hours after the fourth dose (morning) |
| 1 tablet | 12 hours after the fifth dose (evening) |
Side Effects
Common side effects include headache, dizziness, nausea, vomiting, abdominal pain, and loss of appetite. Rare but serious side effects may occur.
Warning
Not for severe malaria. Use with caution in liver or kidney disease. Dosage adjustments may be necessary.
Important Information
Take it with food or a milky drink for proper absorption. Complete the full course of treatment. Seek medical attention if severe side effects occur.
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