Maxolon Syrup is an oral liquid formulation containing the active ingredient metoclopramide. It is a dopamine receptor antagonist primarily used as an antiemetic and prokinetic agent for treating certain gastric disorders.
Uses
The main uses of Maxolon Syrup include:
- Relief of nausea and vomiting associated with chemotherapy, radiotherapy, surgery, and migraine
- Treatment of gastroesophageal reflux disease (GERD) and gastroparesis (delayed stomach emptying)
- Facilitating small bowel intubation during diagnostic procedures
- Prevention of aspiration pneumonia in patients with impaired gastric emptying
Benefits
The key benefits of taking Maxolon Syrup are:
- Effectively controls nausea, vomiting, and associated symptoms
- Improves gastric emptying time and peristalsis of the upper gastrointestinal tract
- Facilitates diagnostic and therapeutic GI procedures
- Liquid formulation allows flexible dosing, especially in pediatrics
- Generally well-tolerated when used for short durations
Mechanism of Action
Metoclopramide is a potent dopamine D2 receptor antagonist in the chemoreceptor trigger zone (CTZ). It also enhances the propulsive motility of the upper GI tract and increases lower esophageal sphincter tone.
Dosage
Dosage varies based on the condition and patient’s age. For nausea/vomiting in adults: 10-20mg 3-4 times daily. For gastroparesis: 5-10mg 3-4 times daily before meals. Follow the dosing instructions carefully.
Side Effects
Common side effects include restlessness, drowsiness, fatigue, and diarrhea. Serious but rare effects like tardive dyskinesia, depression, and hyperprolactinemia may occur with prolonged use.
Warnings
It should not be used in patients with intestinal obstruction, hemorrhage, or bleeding. Use with caution in Parkinson’s disease, renal/hepatic impairment, and children. Limit treatment duration as needed.
Important Information
Take Maxolon Syrup as prescribed, with or without food. Do not crush, chew, or break intact tablets. Disclose all other medications to your doctor to avoid interactions. Report any persistent or worsening symptoms promptly.
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