Metaglomide Tablet 500/5mg is an advanced dual-action diabetes medication combining metformin (500mg) and glibenclamide (5mg). This prescription medication offers strategic blood glucose management through its complementary mechanisms, making it a valuable option for adults with type 2 diabetes who require comprehensive glycemic control.
Uses
Metaglomide Tablet is specifically prescribed for adults with type 2 diabetes mellitus who need improved glycemic control. It’s particularly effective when single-drug therapy proves insufficient. The medication helps maintain optimal blood sugar levels throughout the day while promoting better long-term diabetes management.
Benefits
- Provides dual-mechanism blood sugar control
- Reduces hepatic glucose production
- Improves insulin sensitivity in body tissues
- Enhances pancreatic insulin secretion
- Offers convenient once or twice-daily dosing
- Helps achieve better glycemic targets
- May improve treatment compliance
- Cost-effective compared to separate medications
How It Works
Metaglomide works through a synchronized dual-action approach. Metformin reduces glucose production in the liver and enhances insulin sensitivity in muscle tissues. Simultaneously, glibenclamide stimulates pancreatic beta cells to increase insulin production, effectively lowering blood glucose levels.
Duration of Action
The medication typically starts working within 30 minutes of administration. Metformin’s effects last 8-12 hours, while glibenclamide provides coverage for up to 24 hours. Optimal glycemic control is usually achieved within 1-2 weeks of consistent use.
Dosage
Initial dosage typically starts with one tablet daily with breakfast. Based on blood glucose monitoring and physician assessment, this may be increased to one tablet twice daily. Maximum daily dose should not exceed two tablets. Always take with meals to minimize gastrointestinal effects.
Side Effects
Most common side effects include gastrointestinal disturbances such as nausea, diarrhea, and abdominal discomfort. Hypoglycemia may occur, particularly during the initial adjustment period. Serious but rare side effects include lactic acidosis and liver dysfunction.
Warning
Avoid alcohol consumption while taking Metaglomide. Regular kidney and liver function monitoring is essential. Discontinue use and seek immediate medical attention if experiencing severe nausea, vomiting, abdominal pain, or unusual muscle pain.
Pregnancy and Breastfeeding
Not recommended during pregnancy or breastfeeding. Women who become pregnant while taking Metaglomide should consult their healthcare provider immediately to discuss alternative diabetes management options.
Interactions
- May interact with corticosteroids and thyroid medications
- Alcohol can increase risk of lactic acidosis
- NSAIDs may affect blood sugar control
- Beta-blockers can mask hypoglycemia symptoms
- Certain antibiotics may require dose adjustment
Important Information
Store below 30°C in a dry place. Monitor blood glucose regularly. Carry glucose or sugar source for emergency hypoglycemia management. Never adjust dosage without medical supervision. Regular medical check-ups are essential for optimal diabetes management. Report any unusual symptoms to your healthcare provider promptly.
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