Moduretic Tablet (5/50mg) combines Amiloride (5mg) and Hydrochlorothiazide (50mg) to provide effective treatment for hypertension and fluid retention. This dual-action medication helps manage blood pressure while maintaining potassium balance.
Uses
Moduretic Tablet is primarily used to treat hypertension, edema, and congestive heart failure. It’s particularly effective for patients who need diuretic therapy without potassium depletion.
Benefits
- Controls high blood pressure effectively
- Reduces excess fluid retention
- Maintains potassium balance
- Prevents electrolyte imbalance
- Manages congestive heart failure symptoms
- Reduces swelling in legs and ankles
- Provides dual mechanism of action
- Improves cardiovascular health
- Offers convenient once-daily dosing
How It Works
Moduretic combines two diuretics: Hydrochlorothiazide increases water and salt excretion, while Amiloride helps retain potassium. This unique combination effectively reduces blood pressure and edema while preventing potassium loss.
Duration of Action
Effects typically begin within 2 hours of administration. Diuretic effect peaks in 6-8 hours. Blood pressure reduction becomes optimal after 2-3 weeks of regular use.
Dosage
| Condition | Initial Dose | Maintenance | Timing |
|---|---|---|---|
| Hypertension | 1 tablet | 1-2 tablets | Once daily |
| Edema | 1-2 tablets | As needed | Once daily |
| Elderly | 1/2 tablet | As directed | Once daily |
Side Effects
Common side effects may include:
- Increased urination
- Electrolyte imbalance
- Mild dizziness
- Headache
- Dry mouth
Warning
Monitor electrolyte levels regularly. Seek immediate medical attention if experiencing severe dizziness, muscle weakness, or irregular heartbeat.
Pregnancy and Breastfeeding
Not recommended during pregnancy or breastfeeding. Discuss alternative treatments with your healthcare provider if you are pregnant or planning pregnancy.
Interactions
- May interact with ACE inhibitors/ARBs
- Could affect lithium levels
- Possible interaction with NSAIDs
- May affect diabetes medications
- Could interact with potassium supplements
Precautions
Take early in the day to avoid nighttime urination. Regular monitoring of blood pressure and electrolytes is essential. Stay adequately hydrated. Avoid excessive sun exposure.
Important Information
Moduretic Tablet requires consistent monitoring of blood pressure and electrolyte levels. Take the medication exactly as prescribed. Do not adjust the dose without consulting your healthcare provider.
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