Orelox Tablet 200mg contains cefpodoxime, a third-generation cephalosporin antibiotic. This broad-spectrum medication effectively treats various bacterial infections, offering a convenient twice-daily dosing regimen for improved patient compliance.
Uses
Orelox Tablet 200mg is primarily used to treat:
- Upper and lower respiratory tract infections
- Typhoid fever
- Urinary tract infections
- Skin and soft tissue infections
- Pharyngitis and tonsillitis
- Acute otitis media
- Uncomplicated gonorrhea
Benefits
- Broad-spectrum antibacterial activity
- Convenient twice-daily dosing
- Generally well-tolerated with a favorable safety profile
- Effective against many common bacterial pathogens
- Can be taken with or without food
- Suitable for both adults and children (with appropriate dosage adjustments)
How It Works
Cefpodoxime interferes with bacterial cell wall synthesis by binding to penicillin-binding proteins. This action leads to the inhibition of cell wall formation, causing bacterial cell lysis and death. The drug’s broad spectrum of activity makes it effective against many gram-positive and gram-negative bacteria.
Duration of Action
Orelox Tablet 200mg reaches peak plasma concentrations within 2-3 hours after oral administration. The drug has a half-life of approximately 2-3 hours in adults with normal renal function. The antibiotic effect typically lasts for 12 hours, allowing for twice-daily dosing.
Dosage
The usual adult dose is 200mg twice daily for 7-14 days, depending on the type and severity of infection. For children, the dosage is based on body weight, typically 5mg/kg twice daily. Always follow your healthcare provider’s instructions regarding dosage and duration of treatment.
Side Effects
Common side effects may include:
- Nausea and vomiting
- Diarrhea
- Abdominal pain
- Headache
- Skin rash
Rare but serious side effects can include severe allergic reactions and Clostridium difficile-associated diarrhea. If you experience any severe or persistent side effects, contact your healthcare provider immediately.
Warning
Orelox Tablet 200mg should be used with caution in patients with a history of penicillin or cephalosporin allergy. Patients with severe renal impairment may require dosage adjustment. Always inform your healthcare provider about any allergies or medical conditions before starting treatment.
Pregnancy and Breastfeeding
Orelox Tablet 200mg is generally considered safe during pregnancy (Pregnancy Category B). However, it should be used only when clearly needed and under medical supervision. The drug is excreted in breast milk, so caution is advised when using it while breastfeeding.
Interactions
- May reduce the effectiveness of oral contraceptives
- Can increase the risk of bleeding when taken with anticoagulants
- May interfere with certain laboratory tests, including tests for glucose in urine
Important Information
Complete the full course of antibiotics as prescribed, even if symptoms improve before the course is finished. This helps prevent the development of antibiotic-resistant bacteria. Take Orelox Tablet 200mg at evenly spaced intervals to maintain consistent blood levels. If you miss a dose, take it as soon as you remember, but skip it if it’s almost time for your next dose. Never double up on doses to make up for a missed one. Stay hydrated and inform your doctor if diarrhea persists or becomes severe during treatment.
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