P alaxin Suspension 60ml (Antimalaria)

P alaxin Suspension is an innovative antimalarial medication that combines two active ingredients: piperaquine and dihydroartemisinin. This combination therapy is designed to effectively treat uncomplicated malaria caused by the Plasmodium falciparum parasite, a major cause of severe and potentially life-threatening malaria cases globally.

Uses

P alaxin Suspension is indicated for the treatment of acute, uncomplicated Plasmodium falciparum malaria in adults and children weighing at least 5 kilograms. It is beneficial in areas where malaria parasites have developed resistance to other antimalarial drugs, making it an important tool in the fight against this deadly disease.

Benefits

P alaxin Syrup offers several benefits in the treatment of uncomplicated Plasmodium falciparum malaria:

1. Combination therapy: By combining two different antimalarial drugs with different mechanisms of action, P alaxin Suspension provides a more effective and robust treatment approach, reducing the risk of drug resistance development.
2. Rapid clearance of parasites: Dihydroartemisinin, one of the active ingredients, rapidly reduces the number of circulating malaria parasites in the bloodstream, providing rapid symptom relief.
3. Extended clearance: Piperaquine, the other active ingredient, has a longer half-life and helps clear any remaining parasites from the body, preventing recrudescence (relapse) of the infection.
4. Convenience: P alaxin Suspension is a liquid formulation, making it easier to administer, especially to children or patients who have difficulty swallowing tablets or capsules.

Mechanism of Action

P alaxin Suspension combines two antimalarial compounds with different mechanisms of action:

1. Dihydroartemisinin: This compound belongs to the artemisinin class of drugs and works by disrupting the malaria parasite’s metabolism, causing oxidative stress and ultimately leading to parasite death.
2. Piperaquine: A bisquinoline compound, piperaquine interferes with the detoxification process of the malaria parasite, accumulating in the parasite’s digestive vacuole and causing further damage.

By combining these two compounds, P alaxin Suspension provides a potent one-two punch against the malaria parasite, making it more difficult for resistance to develop.

Dosage

1. A child weighing 5kg takes 12.5ml once daily.
2. A child weighing 7kg takes 17.5ml once daily.
3. A child weighing 10kg takes 25ml once daily.

The dosage of P alaxin Suspension is based on the patient’s body weight and should be administered as a once-daily dose for three consecutive days. It is essential to follow the prescribed dosage and duration of treatment to ensure complete clearance of the malaria parasites.

Side Effects

Like most medications, P alaxin Suspension may cause side effects. Common side effects may include:

• Gastrointestinal disturbances, such as nausea, vomiting, and abdominal pain
• Headache
• Dizziness
• Rash or skin reactions
• Muscle or joint pain

Serious but rare side effects may include:

• Allergic reactions
• Heart rhythm abnormalities (QT prolongation)
• Liver or kidney dysfunction

Warning

P alaxin Syrup should be used with caution in patients with known allergies to any of its ingredients or to other antimalarial drugs. It should also be used cautiously in patients with pre-existing liver or kidney impairment, as dose adjustments may be necessary.

Important Information

P alaxin Suspension is a prescription medication and should only be used under the guidance of a qualified healthcare professional with experience in treating malaria. Patients should provide their complete medical history, including any allergies, current medications, and underlying conditions, to ensure safe and effective use of the medication.