Parlodel 2.5mg contains bromocriptine, a potent dopamine receptor agonist that effectively regulates prolactin levels and hormonal balance. This prescription medication is widely used in endocrine disorders and certain Parkinson’s disease cases, offering targeted therapeutic benefits through its specialized mechanism of action.
Uses
Parlodel is prescribed for various endocrine and neurological conditions, including hyperprolactinemia, prolactin-dependent breast disorders, acromegaly, and as adjunctive therapy in Parkinson’s disease. It’s also used to prevent breast engorgement post-partum when breastfeeding is contraindicated.
Benefits
- Effectively reduces elevated prolactin levels
- Suppresses unwanted lactation
- Helps manage menstrual irregularities
- Reduces symptoms of acromegaly
- Improves motor function in Parkinson’s disease
- Treats prolactin-secreting tumors
- Regulates hormonal imbalances
- Provides fertility support in certain cases
How It Works
Parlodel acts by stimulating dopamine D2 receptors in the brain, particularly in the pituitary gland. This action suppresses prolactin secretion and normalizes growth hormone levels. In Parkinson’s disease, it enhances dopaminergic activity, improving motor function.
Duration of Action
Initial effects can be observed within 1-2 hours of administration. Therapeutic benefits typically develop over 2-3 weeks of consistent use. For prolactin-related conditions, maximum effectiveness is usually achieved within 6-8 weeks of treatment initiation.
Dosage
Start with 1.25mg (half tablet) daily with meals, gradually increasing to 2.5-5mg daily based on response and tolerance. Maximum daily dose varies by condition. Take with food to minimize gastrointestinal effects. Dosing schedule depends on the specific condition being treated.
Side Effects
Common side effects include nausea, dizziness, headache, and fatigue. These typically improve with continued use. More serious side effects may include orthostatic hypotension, mood changes, and compulsive behaviors. Initial side effects often diminish as the body adjusts to the medication.
Warning
Start treatment gradually to minimize side effects. Monitor blood pressure regularly, especially when starting therapy. Avoid sudden position changes to prevent dizziness. Patients with cardiovascular conditions require close monitoring. Discontinue and seek immediate medical attention if experiencing severe headaches or vision changes.
Pregnancy and Breastfeeding
Generally contraindicated during pregnancy unless specifically prescribed for fertility treatment. Not recommended during breastfeeding as it suppresses lactation. Women planning pregnancy should discuss timing of conception with their healthcare provider.
Interactions
- May interact with antipsychotic medications
- Caution with blood pressure medications
- Interaction risk with ergot derivatives
- Effects altered by macrolide antibiotics
- May interact with certain antifungal drugs
Important Information
Take exactly as prescribed. Store below 25°C in a dry place, protected from light. Regular medical monitoring is essential. Report any unusual symptoms or behavioral changes promptly. Don’t stop treatment abruptly without medical supervision. Carry identification indicating use of this medication in case of emergency.
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