Rocephin Injection IV 1G (Ceftriaxone)

Rocephin Injection IV 1G contains ceftriaxone, a third-generation cephalosporin antibiotic. This potent medication is administered intravenously to treat a wide range of serious bacterial infections, offering extended-spectrum activity against both gram-positive and gram-negative bacteria.

Uses

Rocephin Injection IV 1G is used to treat severe bacterial infections, including lower respiratory tract infections, urinary tract infections, skin and soft tissue infections, bone and joint infections, meningitis, and septicemia. It’s also used for surgical prophylaxis and in the management of neutropenic patients with fever suspected to be due to bacterial infection.

Benefits

• Broad-spectrum antibiotic coverage
• Effective against many resistant bacteria
• Treats severe and life-threatening infections
• Once-daily dosing in many cases
• Long half-life allowing for extended dosing intervals

How It Works

Ceftriaxone in Rocephin Injection IV 1G works by interfering with bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs), disrupting the bacterial cell wall structure. This action leads to cell wall weakening and eventual bacterial cell death, effectively eliminating the infection.

Dosage

The dosage of Rocephin Injection IV 1G varies depending on the type and severity of infection, patient’s age, weight, and renal function. Typical adult dosages range from 1 to 2 grams once daily or in divided doses. Always follow your healthcare provider’s instructions regarding dosage and administration.

Side Effects

Common side effects may include injection site reactions, diarrhea, nausea, and rash. More serious side effects, though rare, can include severe allergic reactions, blood disorders, and gallbladder problems. Seek immediate medical attention if you experience any severe or unusual symptoms.

Warning

Hypersensitivity reactions, including anaphylaxis, can occur. Use with caution in patients with a history of penicillin allergy. Prolonged use may result in overgrowth of non-susceptible organisms. Monitor for signs of superinfection. Caution is advised in patients with hepatic or renal impairment.

Pregnancy and Breastfeeding

Rocephin Injection IV 1G should be used during pregnancy only if clearly needed. Ceftriaxone is excreted in human milk in low concentrations. Caution should be exercised when administering to nursing mothers. Consult your healthcare provider for guidance.

Interaction

• May increase the anticoagulant effect of warfarin
• Potential interaction with calcium-containing solutions
• Can interfere with certain lab tests, including Coombs test
• May enhance the nephrotoxic effects of other medications

Important Information

Inform your healthcare provider about all medications, allergies, and medical conditions before receiving Rocephin Injection IV 1G. This medication is for hospital or clinical use and should be administered by a healthcare professional. Complete the full course of treatment as prescribed, even if symptoms improve, to prevent the development of antibiotic-resistant bacteria. Adequate hydration is important during treatment to help prevent kidney stones.