Sporidex Suspension 125mg is a first-generation cephalosporin antibiotic in an oral suspension form. It provides broad-spectrum antibacterial activity while ensuring optimal bioavailability and therapeutic effectiveness, particularly suitable for pediatric use.
Uses
Sporidex Suspension 125mg effectively treats various bacterial infections including respiratory tract infections such as bronchitis and pneumonia, ear infections (otitis media), skin and soft tissue infections like cellulitis and impetigo, urinary tract infections, and bone and joint infections (osteomyelitis).
Benefits
- Broad-spectrum activity against gram-positive and gram-negative bacteria
- Excellent tissue penetration for optimal delivery to infection sites
- Favorable safety profile with lower risk of adverse effects
- Convenient oral suspension formulation improving patient compliance
- Suitable for pediatric patients and those who cannot swallow tablets
- Rapid onset of action for timely relief
- Well-established efficacy profile
- High oral bioavailability
How It Works
Sporidex Suspension works by disrupting bacterial cell wall synthesis. Cefalexin inhibits enzymes responsible for cross-linking the peptidoglycan layer of bacterial cell walls, leading to structural weakness, cell lysis, and bacterial death.
Duration of Action
The antibiotic reaches peak plasma concentrations within 1 hour after administration. Its effects typically last 6-8 hours, with a half-life of approximately 1 hour in patients with normal renal function.
Dosage
| Category | Dosage Instructions | Maximum Daily Dose |
|---|---|---|
| Infants (Under 1 year) | 2.5ml every 6 hours | 40 mg/kg |
| Children (1–6 years) | 5ml every 6 hours | 1 gram |
| Children (7–12 years) | 10ml every 6 hours | 2 grams |
| Adolescents (12 years and above) | 10–20ml every 6 hours (based on severity of infection) | 4 grams |
| Adults | 500mg every 6–12 hours (equivalent to 20ml every 6 hours or 40ml every 12 hours) | 4 grams |
Warnings
Do not use in patients with known hypersensitivity to cephalosporin antibiotics. Use with caution in patients with penicillin allergy due to potential cross-reactivity. Prolonged use may result in superinfection. Discontinue if significant adverse reactions occur.
Side Effects
Common side effects may include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal pain. Allergic reactions ranging from skin rashes to anaphylaxis may occur in susceptible individuals. Transient liver enzyme elevations and changes in blood cell counts have been reported.
Pregnancy and Breastfeeding
Sporidex Suspension should be used during pregnancy only if clearly needed. Cefalexin passes into breast milk in small amounts. Consult a healthcare provider before use during pregnancy or breastfeeding.
Interactions
- Probenecid (increases cefalexin blood levels)
- Metformin (may affect blood glucose control)
- Oral contraceptives (potential reduced effectiveness)
- Warfarin (possible enhanced anticoagulant effect)
- Nephrotoxic drugs (increased risk of kidney damage)
- Bacteriostatic antibiotics (may reduce efficacy)
Precautions
Complete the full prescribed course even if symptoms improve. Shake well before each use. Store suspension in refrigerator after reconstitution. Use within 14 days. Monitor renal function in patients with kidney impairment. Adjust dosage in patients with severe renal insufficiency.
Important Information
Sporidex Suspension should be used judiciously to prevent antibiotic resistance. Take at evenly spaced intervals to maintain consistent antibiotic levels. This medication treats bacterial infections only, not viral infections. Report persistent diarrhea as it may indicate a serious condition requiring immediate medical attention.
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