Synergo Tablet 0.5mg (Carbogoline ) x8

Synergo tablet contains cabergoline, a potent dopamine agonist primarily used to treat hyperprolactinemia and pituitary tumors. This medication effectively regulates prolactin, a hormone crucial for lactation and other bodily functions. By addressing abnormally high prolactin levels, Synergo helps prevent associated health issues like infertility, sexual dysfunction, and bone density loss.

Uses

Synergo tablet is predominantly prescribed for treating hyperprolactinemia disorders, lowering elevated prolactin levels affecting hormone regulation, shrinking benign prolactinomas, and managing certain menstrual disorders and infertility issues related to high prolactin.

Benefits

• Effectively regulates and restores normal prolactin function
• Lowers excessively high prolactin levels
• Relieves symptoms associated with hyperprolactinemia
• Improves fertility in both men and women
• Helps increase libido and sexual function
• Prevents bone mineral loss associated with high prolactin levels
• May reduce the size of pituitary tumors (prolactinomas)

How It Works

Cabergoline, the active ingredient in Synergo, functions as a dopamine agonist. It mimics the action of dopamine by stimulating dopamine D2 receptors in the brain, particularly in the pituitary gland. This stimulation leads to a reduction in prolactin release from the pituitary, effectively lowering prolactin levels in the bloodstream and alleviating associated symptoms.

Dosage

The typical dosage regimen for Synergo is a starting dose of 0.5mg once or twice weekly, which can be gradually increased by 0.5mg weekly at monthly intervals, up to a maximum dose of 2mg 2-3 times per week. Always follow your doctor’s prescription, as dosage may vary based on individual patient response and prolactin levels.

Duration of Action

Synergo has a long-lasting effect due to its extended half-life. A single dose can suppress prolactin levels for up to 14 days. However, the full therapeutic effect may take several weeks to months to achieve. Regular monitoring of prolactin levels is essential to assess the medication’s effectiveness and adjust the dosage if needed.

Side Effects

Common side effects of Synergo may include nausea, vomiting, dizziness, headaches, fatigue, weakness, constipation, abdominal pain, and breast pain or tenderness. Most side effects are mild and tend to diminish over time. However, if you experience severe or persistent side effects, consult your healthcare provider immediately.

Warning

Synergo should not be used in patients with uncontrolled hypertension, history of heart valve disorders, pulmonary or retroperitoneal fibrosis, or during pregnancy (unless specifically prescribed by a doctor). Patients with a history of cardiovascular disease or Raynaud’s syndrome should use this medication with caution.

Pregnancy and Breastfeeding

Synergo is generally not recommended during pregnancy unless the potential benefits outweigh the risks. It can suppress lactation, so it’s typically not used by women who wish to breastfeed. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Interactions

• May interact with other dopamine agonists or antagonists
• Potential interaction with certain antipsychotic medications
• Can enhance the effects of alcohol and increase the risk of side effects
• May interact with metoclopramide and domperidone
• Possible interaction with certain antibiotics and antifungal medications

Important Information

Regular monitoring of prolactin levels and pituitary gland size (if applicable) is essential during treatment. Inform your doctor immediately if you experience worsening breathlessness, chest pain, or ankle swelling, as these may indicate serious heart complications. Some patients may experience impulse control disorders while taking Synergo. Do not stop taking Synergo abruptly without consulting your healthcare provider. Store the medication in a cool, dry place away from direct sunlight and out of reach of children.