Zinnat Suspension (Cefuroxime) 125mg/50ml

Zinnat Suspension contains Cefuroxime, a second-generation cephalosporin antibiotic. This oral suspension formulation effectively combats various bacterial infections in both adults and children, providing a convenient alternative for those who have difficulty swallowing tablets.

Uses

Zinnat Suspension treats a range of bacterial infections including respiratory tract infections (bronchitis, pneumonia), urinary tract infections, and skin and soft tissue infections. It’s also used prophylactically for certain surgical procedures. The suspension formulation makes it suitable for both adults and children.

Benefits

• Broad-spectrum antibiotic effective against many bacterial strains
• Convenient oral suspension for easy administration
• Ideal for patients with difficulty swallowing solid medications
• Reaches therapeutic levels quickly for prompt symptom relief
• Suitable alternative for some patients with penicillin allergies
• Established safety profile in pediatric populations
• Effective against both gram-positive and gram-negative bacteria
• Compatible with many other medications
• Once reconstituted, maintains stability for recommended period

How It Works

Cefuroxime in Zinnat Suspension disrupts bacterial cell wall synthesis by binding to specific proteins called penicillin-binding proteins. This weakens the bacterial cell wall, causing it to rupture and leading to bacterial death. The medication specifically targets the structural integrity of susceptible bacteria while sparing human cells.

Dosage

Take Zinnat Suspension after meals to enhance absorption. Complete the full prescribed course, even if symptoms improve.

Duration of Action

Zinnat Suspension begins working within 1-2 hours after administration. The antibiotic reaches maximum concentration in the bloodstream within 2-3 hours. Each dose provides therapeutic levels for approximately 12 hours, which is why twice-daily dosing is typical. Clinical improvement is usually observed within 48-72 hours of starting treatment.

Side Effects

Common side effects include mild diarrhea, nausea, vomiting, and abdominal discomfort. Less common effects may include headache, dizziness, and temporary changes in taste. Rare but serious side effects include allergic reactions, severe diarrhea, or unusual bleeding/bruising. Contact a healthcare provider if side effects persist or worsen.

Warning

Do not use Zinnat Suspension if you have a known allergy to cephalosporin antibiotics. Use with caution in patients with kidney impairment, as dosage adjustments may be needed. Prolonged use may result in secondary infections. Discontinue and seek medical attention if severe allergic reactions, persistent diarrhea, or other serious side effects occur.

Pregnancy and Breastfeeding

Zinnat Suspension is generally considered safe during pregnancy when clearly needed. It passes into breast milk in small amounts. While adverse effects in breastfed infants are rare, monitor for diarrhea, thrush, or allergic reactions. Consult your healthcare provider before using during pregnancy or while breastfeeding.

Interaction

• May reduce effectiveness of oral contraceptives
• Potential increased risk of bleeding with anticoagulants
• Possible false positive results in certain urine glucose tests
• Probenecid may increase blood levels of cefuroxime
• Antacids may reduce absorption if taken simultaneously

Precaution

Store reconstituted suspension in refrigerator. Shake well before each use. Patients with history of gastrointestinal disease should be monitored for colitis. Those with renal impairment may require dosage adjustment. Complete the entire prescribed course to prevent bacterial resistance. Inform all healthcare providers about ongoing antibiotic treatment.

Important Information

Complete the entire prescribed course of Zinnat Suspension even after symptoms improve to prevent antibiotic resistance. Take the medication at evenly spaced intervals for optimal effectiveness. After reconstitution, the suspension remains stable for 10 days when refrigerated. Discard any unused medication after this period. Never share antibiotics with others, even if symptoms appear similar.