Arenax Plus Forte Tablet 80/480mg x6

Arenax Plus Forte Tablet combines Artemether and Lumefantrine, offering a potent artemisinin-based combination therapy (ACT) for malaria treatment. This prescription medication provides rapid and effective action against Plasmodium falciparum, including multidrug-resistant strains, making it a crucial tool in malaria management.

Uses

Arenax Plus Forte is primarily used for:

• Treatment of acute, uncomplicated malaria caused by Plasmodium falciparum
• Management of mixed infections including P. falciparum

Benefits

• Rapid clearance of malaria parasites
• Effective against multidrug-resistant P. falciparum strains
• Reduces risk of treatment failure and recrudescence
• Combination therapy helps prevent development of resistance
• Well-tolerated in most patients
• Suitable for both adults and children (weight-based dosing)

How It Works

Artemether rapidly reduces parasite biomass, while Lumefantrine eliminates residual parasites. Artemether interferes with parasite protein synthesis, and Lumefantrine disrupts parasite mitochondrial function. This dual action ensures thorough parasite clearance and prevents recrudescence.

Dosage

Dosage is based on body weight. Typically, a 3-day regimen is prescribed:

• Day 1: Initial dose, followed by second dose after 8 hours
• Day 2 and 3: Two doses daily, 12 hours apart

Always follow your healthcare provider’s specific instructions.

Side Effects

Common side effects may include:

• Headache
• Dizziness
• Nausea and vomiting
• Abdominal pain
• Loss of appetite
• Sleep disturbances

Severe side effects are rare but require immediate medical attention.

Warning

• Not recommended in first trimester of pregnancy unless alternatives are unavailable
• Use caution in patients with cardiac disorders or electrolyte imbalances
• Not for prophylactic use
• Avoid grapefruit juice during treatment

Interaction

Arenax Plus Forte may interact with:

• CYP3A4 inhibitors or inducers
• Drugs that prolong QT interval
• Antiretroviral medications
• Hormonal contraceptives (may reduce efficacy)

Inform your healthcare provider about all medications you’re taking.

Important Information

Complete the full course of treatment even if symptoms improve. Take with food or milk to enhance absorption. If vomiting occurs within 1 hour of dosing, repeat the dose. This medication does not prevent malaria transmission to others. Continue using protective measures against mosquito bites. Seek medical attention if fever persists or returns within 28 days after treatment. Regular monitoring of liver function and complete blood count may be necessary during treatment.