Co-Diovan 160mg/25mg (Valsartan/Hydrochlorothiazide) x28

Co-Diovan 160mg/25mg combines Valsartan (160mg) and Hydrochlorothiazide (25mg) to effectively manage hypertension. This dual-action medication relaxes blood vessels and reduces heart workload, offering comprehensive blood pressure control for patients requiring combination therapy.

Uses

Co-Diovan is primarily used to treat hypertension in patients who haven’t achieved adequate blood pressure control with single-drug therapy. It’s particularly effective for managing moderate to severe high blood pressure and reducing cardiovascular risks associated with elevated blood pressure.

Benefits

• Lowers high blood pressure effectively
• Reduces risk of heart attacks and strokes
• Improves overall cardiovascular health
• Combines two proven medications in one tablet
• More convenient than taking separate medications
• May provide better blood pressure control than monotherapy
• Reduces pill burden for patients
• Enhances medication compliance
• Provides 24-hour blood pressure control

How It Works

Valsartan blocks angiotensin II receptors, preventing blood vessel constriction and aldosterone release. Hydrochlorothiazide acts as a thiazide diuretic, increasing sodium and water excretion through the kidneys. Together, they lower blood pressure by relaxing blood vessels and reducing fluid volume in the circulatory system.

Dosage

Take Co-Diovan at the same time each day, with or without food. Swallow whole with water.

Duration of Action

Co-Diovan 160mg/25mg begins working within 2-4 hours of administration. Maximum blood pressure reduction typically occurs within 4-6 weeks of regular use. The medication provides 24-hour blood pressure control with once-daily dosing, maintaining consistent therapeutic levels throughout the day.

Side Effects

Common side effects include headache, dizziness, fatigue, and diarrhea. Some patients may experience dry cough, muscle cramps, or increased urination. Most side effects are mild and diminish as the body adjusts to the medication.

Warning

Co-Diovan 160mg/25mg may cause severe hypotension, especially in volume-depleted patients. Not suitable for patients with anuria, severe kidney or liver disease, or those allergic to sulfonamides. May cause fetal harm during pregnancy. Discontinue if angioedema occurs. Monitor kidney function and electrolytes regularly.

Pregnancy and Breastfeeding

Co-Diovan is contraindicated during pregnancy due to risk of fetal harm, including kidney problems and death. Women of childbearing age should use effective contraception. Both components may pass into breast milk, so breastfeeding is not recommended during treatment.

Interaction

• May increase lithium levels leading to toxicity
• NSAIDs may reduce effectiveness and increase kidney damage risk
• Potassium supplements may cause dangerous hyperkalemia
• Alcohol may enhance hypotensive effects
• Diabetes medications may require dose adjustments
• ACE inhibitors should not be used concurrently

Precaution

Monitor blood pressure, kidney function, and electrolyte levels regularly. Use caution in patients with kidney disease, liver impairment, heart failure, or diabetes. Avoid dehydration and excessive heat exposure. Inform all healthcare providers about Co-Diovan use before procedures or starting new medications.

Important Information

Co-Diovan 160mg/25mg helps manage but does not cure hypertension. Continue taking even if feeling well, as high blood pressure often has no symptoms. Regular monitoring and lifestyle modifications including diet and exercise enhance effectiveness. Store at room temperature and keep out of reach of children. Do not stop suddenly without medical consultation.