Lofnac Suppository (Diclo) 100mg x10

Lofnac Suppository 100mg is a non-steroidal anti-inflammatory drug (NSAID) in suppository form containing Diclofenac Sodium. This formulation provides effective pain relief and anti-inflammatory action through rectal administration, particularly useful when oral medication is not suitable.

Uses

Lofnac Suppository treats acute pain, chronic pain conditions, post-operative pain, rheumatic disorders, and inflammatory conditions. It’s particularly effective when immediate pain relief is needed or oral administration is not possible.

Benefits

• Rapid pain relief
• Bypasses digestive system
• Reduces inflammation effectively
• Suitable for post-operative use
• Alternative to oral medication
• Long-lasting pain control
• Minimal gastric irritation
• High bioavailability
• Convenient administration
• Reliable therapeutic effect

How It Works

Diclofenac works by inhibiting prostaglandin synthesis through blocking cyclooxygenase enzymes (COX-1 and COX-2). This reduces inflammation, pain, and fever while providing effective analgesic relief.

Duration of Action

Onset of action begins within 30 minutes. Peak effect achieved within 1-2 hours. Pain relief typically lasts 6-8 hours. Maximum therapeutic benefit observed with regular use as prescribed.

Dosage

Adults: One 100mg suppository daily, preferably at bedtime. Maximum daily dose should not exceed 100mg. Insert rectally following proper hygiene procedures. Do not exceed recommended dose.

Side Effects

Common effects include rectal irritation, bleeding, or discomfort. Less common effects include headache, dizziness, and gastrointestinal disturbances. Report any unusual bleeding or severe reactions.

Warning

Avoid in patients with rectal inflammation or recent rectal bleeding. Use cautious in elderly patients. Regular monitoring required for long-term use. Immediate medical attention if severe rectal pain or bleeding occurs.

Pregnancy and Breastfeeding

Not recommended during third trimester of pregnancy. Use with caution during first and second trimesters. Consult healthcare provider before use during breastfeeding.

Interactions

• May interact with blood thinners
• Potential interaction with other NSAIDs
• Can affect blood pressure medications
• Interacts with corticosteroids
• May affect kidney medications
• Possible interaction with lithium
• Can interact with diuretics
• May affect methotrexate levels
• Potential interaction with SSRIs
• Could affect cardiac medications

Important Information

Insert after bowel movement when possible. Maintain proper hygiene during administration. Store at room temperature away from heat. Complete prescribed course of treatment. Report any unusual symptoms promptly. Regular monitoring may be required for long-term use.