Betavate-C Cream (Betamethasone) x20g

Betavate-C Cream is a combination topical medication containing Betamethasone, a potent corticosteroid, and Clioquinol, an antimicrobial agent. This dual-action formulation effectively treats inflammatory skin conditions complicated by bacterial or fungal infections. It Also provides effective treatment for various dermatological conditions with concurrent infection.

Uses

Betavate-C Cream treats inflammatory skin disorders complicated by secondary bacterial or fungal infections. Common conditions include infected eczema, infected dermatitis, infected psoriasis, infected seborrheic dermatitis, infected intertrigo, and infected otitis externa. It also treats secondarily infected insect bites, minor wounds, and burns.

Benefits

• Potent anti-inflammatory action
• Effective against bacterial infections
• Active against fungal infections
• Reduces itching and discomfort
• Decreases skin redness and swelling
• Relieves infection-related symptoms
• Dual-action formulation requires single application
• Convenient cream base for easy application

How It Works

Betavate-C Cream works through a dual mechanism. Betamethasone binds to glucocorticoid receptors, reducing inflammatory chemical production and suppressing immune response. Clioquinol disrupts bacterial and fungal cell metabolism through its iodine content and chelating properties, eliminating infectious agents on the skin surface.

Duration of Action

Anti-inflammatory effects begin within hours of application, with antimicrobial activity starting immediately upon contact. Effects typically last 12-24 hours, requiring application 1-3 times daily depending on condition severity.

Dosage

Condition	Recommended Application	Frequency
Mild infections	Thin layer	Once or twice daily
Moderate infections	Thin layer	Twice daily
Severe conditions	Thin layer	Three times daily
Children	Thin layer	Once or twice daily

Warnings

Prolonged use may cause skin thinning, striae, and increased risk of systemic absorption. Avoid application near eyes, on large areas, under occlusive dressings, or for extended periods without medical supervision. Discontinue if irritation develops or worsens. Not for use on genital or facial areas without specific medical direction.

Side Effects

Local side effects may include skin thinning, burning sensation, irritation, dryness, acne-like eruptions, and hypopigmentation. Prolonged use may lead to skin atrophy, striae, telangiectasia, increased susceptibility to skin infections, and rarely, systemic effects if absorbed in significant quantities.

Pregnancy and Breastfeeding

Use during pregnancy only if potential benefits outweigh risks. Avoid extensive application, prolonged use, or application under occlusion during pregnancy. Not recommended during breastfeeding unless essential, and should not be applied to the breast area if breastfeeding.

Interactions

• Other topical medications (increased absorption)
• Systemic corticosteroids (additive effects)
• CYP3A4 inhibitors (potential increased systemic effects)
• Medications causing photosensitivity (increased reaction risk)
• Topical antibiotics (possible antagonistic effects)
• Occlusive dressings (enhanced absorption)
• Silver-containing products (incompatibility with clioquinol)

Precautions

Apply sparingly to affected areas only. Wash hands thoroughly after application unless treating hand conditions. Avoid contact with eyes or mucous membranes. Do not bandage or cover treated areas unless directed by healthcare provider. Temporary skin discoloration may occur due to clioquinol. Discontinue if condition worsens or shows no improvement after 7 days.

Important Information

Betavate-C Cream may stain skin, hair, and fabric a yellowish color due to clioquinol content. This discoloration is temporary and will wash off. Treatment should be limited to 7-14 days unless specifically directed otherwise by a healthcare professional. Store at room temperature away from heat and moisture.