Crescent Simvastatin 40mg Tablet is a prescription medication belonging to the statin class of drugs. It contains 40mg of simvastatin in each tablet and is packaged in a box of 28 tablets. This medication is primarily used to lower cholesterol levels and reduce the risk of cardiovascular diseases.
Uses
- Lowering high cholesterol levels (LDL and triglycerides)
- Increasing good cholesterol (HDL) levels
- Reducing the risk of heart attack, stroke, and other cardiovascular complications
- Treating certain types of coronary heart disease
- Managing familial hypercholesterolemia in adults and children
Benefits
- Effectively lowers LDL cholesterol and triglycerides
- Raises HDL cholesterol levels significantly
- Reduces risk of cardiovascular events and complications
- Helps prevent atherosclerosis progression
- May slow coronary heart disease advancement
- Convenient once-daily dosing schedule
- Well-established safety and efficacy profile
- Suitable for long-term cholesterol management
How It Works
Crescent Simvastatin inhibits HMG-CoA reductase, the key enzyme responsible for cholesterol production in the liver. By blocking this enzyme, it reduces cholesterol synthesis and increases the liver’s ability to remove LDL cholesterol from the bloodstream, effectively lowering total blood cholesterol levels.
Dosage
Patient Type | Starting Dosage | Maximum Dosage |
---|---|---|
Adults | 20-40mg daily | 80mg daily |
Elderly | 20mg daily | 40mg daily |
Take Crescent Simvastatin once daily in the evening, with or without food, at the same time each day.
Duration of Action
Crescent Simvastatin begins working within hours but significant cholesterol reduction typically occurs within 2-4 weeks of regular use. Peak effects are usually achieved after 4-6 weeks of consistent therapy. The medication’s cholesterol-lowering effects persist for 24 hours per dose.
Side Effects
Common side effects include mild muscle pain, joint discomfort, constipation, and nausea. Rare but serious effects include severe muscle pain, weakness, liver problems, and elevated blood sugar levels. Most side effects are mild and resolve with continued use.
Warning
Crescent Simvastatin can cause serious muscle problems leading to kidney damage. Report unexplained muscle pain, tenderness, or weakness immediately. Avoid large amounts of grapefruit juice. Pregnant women or those planning pregnancy must not take simvastatin due to potential fetal harm.
Pregnancy and Breastfeeding
Crescent Simvastatin is contraindicated during pregnancy and breastfeeding. Women of childbearing age should use effective contraception while taking this medication. If pregnancy occurs, discontinue immediately and consult your healthcare provider about alternative treatments.
Interaction
- May interact with certain antibiotics and antifungal medications
- Can interact with other cholesterol-lowering drugs
- Potential interactions with HIV medications
- Alcohol increases risk of liver problems
- Grapefruit juice increases simvastatin blood concentration
Precaution
Regular blood tests are required to monitor cholesterol levels and liver function. Use caution in patients with liver disease, kidney problems, or muscle disorders. Elderly patients may require lower doses. Inform all healthcare providers about simvastatin use before procedures or new medications.
Important Information
Regular blood tests are necessary to monitor cholesterol levels and liver function while taking Crescent Simvastatin. Inform your doctor about all medications, supplements, and herbal products you are taking. This medication is most effective when combined with a healthy diet and regular exercise. Do not stop taking simvastatin without consulting your doctor, as this may increase your risk of heart attack or stroke. If you miss a dose, take it as soon as you remember, unless it’s almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule.
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