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Dopatab 250mg (Methydopa) x100

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Dopatab is used alone or with other medications to treat high blood pressure. Dopatab works by relaxing blood vessels so blood can flow more easily.


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Dopatab 250mg is a prescription medication containing the active ingredient methydopa. It is a centrally acting alpha-adrenergic agonist primarily used for the management of hypertension (high blood pressure).


The main uses of Dopatab include:

  • Treatment of hypertension, either alone or in combination with other antihypertensive drugs
  • Short-term management of pregnancy-induced hypertension and pre-eclampsia
  • Control of severe hypertension in patients undergoing surgery


Key benefits of taking Dopatab include:

  • Effectively reduces elevated blood pressure levels
  • Decreases excessive catecholamine activity in the brain
  • May have fewer side effects compared to some other antihypertensive classes
  • Suitable for use during pregnancy when other options are limited
  • Available in both tablet and liquid formulations

Mechanism of Action

Methydopa acts centrally on alpha-2 adrenergic receptors in the brain to decrease sympathetic outflow from the vasomotor center. This reduces peripheral vascular resistance, leading to lower blood pressure.


Dosage is individualized based on patient response. Typical starting dose is 250mg two or three times daily, up to a maximum of 3g daily in divided doses. Take with food or liquid to minimize stomach upset.

Side Effects

Common side effects include dry mouth, sedation, dizziness, headache, and gastrointestinal disturbances. Rare but serious side effects like hemolytic anemia, hepatotoxicity or lupus-like syndrome may occur.


Use caution in patients with cerebrovascular disorders, active liver disease, pheochromocytoma or severe renal impairment. Discontinue gradually to avoid rebound hypertension.

Important Information

Take Dopatab regularly as prescribed for optimal blood pressure control. Have regular checkups and blood tests to monitor therapy. Limit alcohol and follow dietary salt restriction. Inform your doctor about all other medications.

  • The usual starting dosage is 50mg taken orally once per day.
  • The effective dosing range is generally between 50-100mg daily.
  • If blood pressure is still not adequately controlled on 50mg, the dosage may be increased to 100mg once daily. This is the maximum daily dose.
  • Losartan should be taken at the same time each day for consistency, preferably in the morning.
  • It can be taken with or without food and should be accompanied by a full glass of water.
  • Patients with impaired liver function usually require dosage adjustments or alternative medications.
  • No dosage adjustment is necessary for elderly patients or those with kidney impairment.
  • If a dose is skipped, take it as soon as possible unless close to the next scheduled time.
  • Do not double doses to make up for missed doses. Simply continue the regular dosing routine.

Always follow the prescribing doctor's directions for individualized losartan dosage guidelines and let them know if blood pressure is not responding adequately after dose titrations.


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