Dopatab 250mg is a prescription medication containing the active ingredient methydopa. It is a centrally acting alpha-adrenergic agonist primarily used for the management of hypertension (high blood pressure).
Uses
The main uses of Dopatab include:
- Treatment of hypertension, either alone or in combination with other antihypertensive drugs
- Short-term management of pregnancy-induced hypertension and pre-eclampsia
- Control of severe hypertension in patients undergoing surgery
Benefits
Key benefits of taking Dopatab include:
- Effectively reduces elevated blood pressure levels
- Decreases excessive catecholamine activity in the brain
- May have fewer side effects compared to some other antihypertensive classes
- Suitable for use during pregnancy when other options are limited
- Available in both tablet and liquid formulations
Mechanism of Action
Methydopa acts centrally on alpha-2 adrenergic receptors in the brain to decrease sympathetic outflow from the vasomotor center. This reduces peripheral vascular resistance, leading to lower blood pressure.
Dosage
Dosage is individualized based on patient response. Typical starting dose is 250mg two or three times daily, up to a maximum of 3g daily in divided doses. Take with food or liquid to minimize stomach upset.
Side Effects
Common side effects include dry mouth, sedation, dizziness, headache, and gastrointestinal disturbances. Rare but serious side effects like hemolytic anemia, hepatotoxicity or lupus-like syndrome may occur.
Warnings
Use caution in patients with cerebrovascular disorders, active liver disease, pheochromocytoma or severe renal impairment. Discontinue gradually to avoid rebound hypertension.
Important Information
Take Dopatab regularly as prescribed for optimal blood pressure control. Have regular checkups and blood tests to monitor therapy. Limit alcohol and follow dietary salt restriction. Inform your doctor about all other medications.
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