Eproxen 500mg is a combination medication containing naproxen (an NSAID) and esomeprazole (a proton pump inhibitor). This dual-action formula provides effective pain relief while protecting the stomach from NSAID-related gastric complications through acid suppression.
Uses
Eproxen 500mg treats acute pain, chronic conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other inflammatory conditions. It’s specifically designed for patients requiring long-term NSAID therapy who are at risk for gastrointestinal complications.
Benefits
- Effective pain and inflammation relief
- Reduces risk of gastric ulcers
- Provides gastroprotection
- Manages chronic arthritic conditions
- Relieves acute musculoskeletal pain
- Once-daily convenient dosing
- Better gastrointestinal tolerance
- Suitable for long-term use
How It Works
Naproxen works by inhibiting COX enzymes, reducing prostaglandin synthesis and inflammation, while esomeprazole reduces stomach acid production by blocking the proton pump in gastric cells, protecting against NSAID-induced gastric damage.
Dosage
| Condition | Dosage | Duration and Frequency |
|---|---|---|
| Arthritis | 1 tablet | Twice daily for up to 6 months |
| Acute Pain | 1 tablet | Twice daily for 5-10 days |
| Chronic Pain | 1 tablet | Twice daily as prescribed |
Duration of Action
Pain relief begins within 1-2 hours of administration. Anti-inflammatory effects build over several days. Gastroprotective action starts within 24 hours. Full therapeutic effect achieved within 3-4 days of regular use.
Side Effects
Common side effects include mild headache, dizziness, and drowsiness. More serious side effects may include cardiovascular events, gastrointestinal bleeding, or kidney problems. Regular monitoring required during long-term use.
Warning
Seek immediate medical attention if experiencing chest pain, shortness of breath, black stools, or severe stomach pain. Not recommended for patients with severe heart disease, recent heart attack, or stroke history.
Pregnancy and Breastfeeding
Contraindicated in late pregnancy due to risk of premature closure of the ductus arteriosus. Not recommended during breastfeeding. Consult healthcare provider for alternative pain management options.
Interactions
- Blood thinners (warfarin, aspirin)
- Antidepressants (SSRIs)
- Other NSAIDs
- ACE inhibitors/ARBs
- Methotrexate
Precautions
Take with food or milk to minimize stomach upset. Avoid alcohol consumption. Monitor blood pressure regularly. Report any unusual bleeding or bruising. Use lowest effective dose for shortest duration needed.
Important Information
Eproxen should be taken only as prescribed. Regular monitoring of kidney and liver function may be necessary during long-term use. Keep all follow-up appointments with healthcare provider. Store at room temperature away from moisture and heat. Do not double dose if a dose is missed. Contact healthcare provider if pain worsens or new symptoms develop.
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