Genevin Tablet 500mg (Griseofulvin) x20

Genevin Tablet 500mg contains Griseofulvin, an antifungal medication specifically designed to treat dermatophyte infections. This systemic antifungal effectively treats fungal infections of skin, hair, and nails that cannot be treated with topical medications alone.

Uses

Genevin Tablet treats severe fungal infections including tinea capitis (scalp ringworm), tinea corporis (body ringworm), tinea pedis (athlete’s foot), tinea unguium (nail fungus), and tinea barbae (beard ringworm). It’s particularly effective for widespread infections or those resistant to topical treatments.

Benefits

• Effectively eliminates dermatophyte fungal infections
• Treats infections resistant to topical antifungals
• Penetrates hair shafts and nail beds effectively
• Prevents spread of fungal infections to others
• Reduces itching, scaling, and inflammation
• Prevents secondary bacterial infections
• Suitable for widespread or severe infections
• Long-lasting therapeutic effects
• Alternative for patients intolerant to other antifungals

How It Works

Genevin works by binding to keratin in newly formed skin, hair, and nail cells, making them resistant to fungal invasion. Griseofulvin disrupts fungal cell division by interfering with microtubule formation, preventing fungal growth and reproduction. The medication accumulates in infected tissues, providing sustained antifungal activity.

Dosage

Take Genevin with a high-fat meal to enhance absorption. Treatment duration varies from 4-12 weeks depending on infection site and severity.

Duration of Action

Genevin begins working within days of starting treatment, though visible improvement may take 2-4 weeks. Hair and scalp infections typically clear within 4-6 weeks, while nail infections require 6-12 months of treatment. The medication remains active in tissues for weeks after discontinuation.

Side Effects

Common side effects include headache, nausea, diarrhea, and mild skin rash. Some patients experience dizziness, fatigue, or metallic taste. Less common effects include photosensitivity, liver enzyme elevation, or blood count changes. Most side effects are mild and resolve with continued treatment.

Warning

Genevin may cause liver toxicity requiring periodic liver function monitoring. This medication increases photosensitivity, making sunburn more likely. Avoid alcohol consumption during treatment as it may cause severe reactions. Genevin can interact with hormonal contraceptives, reducing their effectiveness.

Pregnancy and Breastfeeding

Genevin is contraindicated during pregnancy due to potential birth defects and embryotoxicity. Women of childbearing age should use effective non-hormonal contraception during treatment and for one month after discontinuation. It’s also contraindicated during breastfeeding as it passes into breast milk.

Interaction

• Reduces effectiveness of hormonal contraceptives significantly
• May increase effects of alcohol causing severe reactions
• Possible interaction with warfarin increasing bleeding risk
• May reduce effectiveness when taken with barbiturates
• Potential interaction with cyclosporine reducing its levels

Precaution

Monitor liver function regularly during prolonged treatment. Use sun protection and avoid excessive UV exposure due to increased photosensitivity. Patients with liver disease, lupus, or porphyria require careful monitoring. Complete the full treatment course even if symptoms improve to prevent recurrence.

Important Information

Genevin requires long-term treatment for complete fungal eradication. Regular follow-up appointments are essential to monitor progress and side effects. Maintain good hygiene practices to prevent reinfection. Store at room temperature away from light and moisture. Report any persistent nausea, jaundice, or unusual fatigue to your healthcare provider immediately.