Pregasafe 75mg contains pregabalin, an alpha2delta ligand that modulates overexcited nerves to provide analgesic, anticonvulsant, and anxiolytic effects in neuropathic pain disorders.
Uses
Pregasafe 75mg is specifically indicated for managing diabetic peripheral neuropathy, post-herpetic neuralgia, spinal cord injury pain, and as an adjunct therapy for partial-onset seizures.
Benefits
Key advantages include a significant reduction in neuropathic pain scores within the therapeutic range and decreased seizure frequency with greater patient satisfaction, and improved sleep and mood.
Mechanism of Action
Pregabalin binds to calcium channels, reducing downstream neurotransmitter release to dampen overexcited damaged nerves transmitting pain signals.
Dosage
The starting dose is 75mg twice daily which can be gradually increased up to 300mg daily divided into 2 or 3 doses based on patient response and tolerability.
Warnings
See prompt medical advice for symptoms like swelling, weight gain, vision changes, mood swings, or suicidal thoughts while on treatment.
Important Information
Inform your doctor about kidney disorder history or medications taken before initiating pregabalin therapy. Do not suddenly stop taking this medication.
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