Provera 5mg Tablet (Medroxyprogesterone) x30

Provera 5mg Tablet contains Medroxyprogesterone, a synthetic progestin hormone used to treat menstrual disorders, endometriosis, and as hormone replacement therapy. This medication regulates menstrual cycles and provides contraceptive effects when used appropriately.

Uses

Provera treats irregular menstrual periods, abnormal uterine bleeding, and amenorrhea. It’s used for endometriosis management, hormone replacement therapy in postmenopausal women, and as contraception. Provera also helps treat certain types of kidney or uterine cancer and prevents endometrial hyperplasia.

Benefits

• Regulates irregular menstrual cycles effectively
• Reduces heavy or prolonged menstrual bleeding
• Provides relief from endometriosis symptoms
• Offers long-term contraceptive protection
• Prevents endometrial cancer in postmenopausal women
• Treats secondary amenorrhea successfully
• Reduces menopausal symptoms when combined with estrogen
• Helps manage abnormal uterine bleeding
• Provides hormone balance in various conditions

How It Works

Provera mimics natural progesterone by binding to progesterone receptors in target tissues. It transforms the endometrium from proliferative to secretory phase, regulating menstrual cycles. The medication also suppresses ovulation when used for contraception and counteracts estrogen’s effects on the endometrium in hormone therapy.

Dosage

Take Provera at the same time each day with or without food. Follow prescribed schedule exactly as directed by healthcare provider.

Duration of Action

Provera begins working within hours of administration, with full hormonal effects developing over several days. Menstrual periods typically occur 3-7 days after completing the course. For contraceptive use, effects last throughout the treatment period and gradually reverse after discontinuation.

Side Effects

Common side effects include irregular bleeding, breast tenderness, weight gain, and mood changes. Some patients experience bloating, headache, or nausea. Less common effects include acne, hair loss, or decreased libido. Serious side effects may include blood clots, depression, or liver problems.

Warning

Provera increases risk of blood clots, stroke, and breast cancer, especially in smokers over 35. It may cause significant bone density loss with long-term use. Discontinue immediately if experiencing sudden severe headache, chest pain, or signs of blood clots. Not recommended for women with undiagnosed vaginal bleeding.

Pregnancy and Breastfeeding

Provera is contraindicated during pregnancy as it may cause birth defects. Pregnancy should be ruled out before starting treatment. Small amounts pass into breast milk but are generally considered compatible with breastfeeding. Use reliable contraception during treatment if pregnancy prevention is desired.

Interaction

• May reduce effectiveness of anticoagulant medications
• Possible decreased effects with certain anticonvulsants
• May alter blood glucose levels in diabetic patients
• Could interact with corticosteroids enhancing their effects
• Potential interaction with cyclosporine increasing toxicity risk

Precaution

Use cautiously in patients with diabetes, hypertension, migraine headaches, or history of depression. Monitor blood pressure and glucose levels regularly. Patients with liver disease, kidney problems, or cardiovascular risk factors require careful evaluation. Discontinue if jaundice or significant mood changes occur.

Important Information

Provera requires regular medical monitoring including breast exams and blood pressure checks. Report any unusual vaginal bleeding, severe headaches, or mood changes to your healthcare provider. Store at room temperature away from moisture and heat. This medication may mask onset of menopause and affect bone density with prolonged use.