Xasten Dexamethasone 1mg Tablets are a prescription medication belonging to the corticosteroid class, known for their potent anti-inflammatory properties. This powerful medication is used to treat a wide range of conditions characterized by inflammation, allergic reactions, and immune system disorders.
Uses of Xasten
Xasten Dexamethasone 1mg is used in the treatment of
- Inflammation
- Allergic reactions
- Rheumatoid arthritis and other rheumatic diseases
- Skin diseases
- Eye problems
- Breathing problems
- Bowel disorders
- Cancer
- Immune system disorders
- Prominence for treating severe COVID-19 cases
- Cushing’s syndrome (a disorder of the adrenal glands)
Benefit
- Reduces inflammation effectively
- Helps manage various inflammatory and autoimmune conditions
- Provides relief from symptoms associated with allergic reactions
- Supports the treatment of certain cancers
- Reduces nausea and vomiting associated with chemotherapy
- Treats cerebral edema to reduce pressure in the brain
- Helps manage severe allergic reactions
How It Works
Xasten Dexamethasone enters cells and binds to glucocorticoid receptors, affecting gene expression that controls inflammation. It inhibits inflammatory mediators, reduces white blood cell migration to affected areas, and stabilizes cell membranes. These actions decrease inflammation, immune reactivity, and associated symptoms.
Duration of Action
Effects begin within 1-2 hours of administration. The biological half-life of dexamethasone is 36-54 hours, making it a long-acting corticosteroid. A single dose can provide anti-inflammatory effects for up to 3 days. Treatment duration varies from short courses to long-term therapy depending on the condition.
Dosage
The usual dosage is one tablet by mouth once or twice a day
Condition | Initial Dose | Maintenance Dose |
---|
General inflammation | 0.5-9mg daily | Lowest effective dose |
Severe acute conditions | 10-20mg daily | Taper gradually |
Pediatric use | 0.03-0.3mg/kg daily | Based on response |
Side Effects
Short-term use generally has minimal side effects. Long-term use may cause weight gain, fluid retention, elevated blood sugar, mood changes, and insomnia. Extended treatment can lead to osteoporosis, increased infection risk, adrenal suppression, muscle weakness, and skin changes. Report unusual symptoms to your doctor.
Warning
Abrupt discontinuation after prolonged use can cause withdrawal syndrome or adrenal crisis. Not recommended for patients with systemic fungal infections. Use cautiously in patients with diabetes, hypertension, osteoporosis, glaucoma, or peptic ulcers. May mask infection signs. Can affect growth in children.
Pregnancy and Breastfeeding
Use during pregnancy only if potential benefits outweigh risks. May increase risk of cleft palate if used in first trimester. Can cross the placenta and affect fetal adrenal function. Small amounts pass into breast milk. Consult your healthcare provider if pregnant or breastfeeding.
Interactions
- May reduce effectiveness of antidiabetic medications
- Can decrease effects of anticoagulants like warfarin
- Increases risk of gastrointestinal bleeding with NSAIDs
- Certain antibiotics and antifungals may increase dexamethasone levels
- May reduce response to vaccines and toxoids
Precaution
Take with food to reduce stomach irritation. Do not stop treatment suddenly without medical guidance. Inform all healthcare providers about dexamethasone use. Monitor for signs of infection or adrenal insufficiency. Carry medical identification if on long-term therapy. Regular medical check-ups required during extended use.
Important Information
Xasten Dexamethasone is a powerful medication that should be used at the lowest effective dose for the shortest duration possible. Follow your doctor’s instructions precisely. Do not adjust dosage without consultation. Store at room temperature away from moisture and heat. Keep out of reach of children. Not for use in viral infections without bacterial complications.
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