Kotase Tablet contains Bromelain 20,000 units (40mg) and Crystalline Trypsin 2,500 units (1mg). This proteolytic enzyme combination reduces inflammation, promotes healing, and helps break down proteins to alleviate pain and swelling.
Uses
Kotase Tablet treats inflammatory conditions including post-surgical swelling, sports injuries, arthritis, and tissue trauma. It aids wound healing, reduces bruising, and alleviates pain associated with inflammatory disorders. The medication is commonly prescribed after dental procedures or orthopedic surgeries.
Benefits
- Reduces inflammation and tissue swelling effectively
- Accelerates wound healing and tissue repair
- Provides natural pain relief without NSAIDs
- Minimizes post-surgical bruising and edema
- Improves mobility in inflammatory joint conditions
- Enhances protein digestion when taken with meals
- Reduces recovery time after injuries
- Well-tolerated with minimal side effects
- Supports immune system function
How It Works
Bromelain, derived from pineapple stems, breaks down fibrin clots and inflammatory proteins while enhancing circulation. Crystalline Trypsin aids protein digestion and reduces inflammatory mediators. Together, these enzymes promote faster healing by removing damaged tissue proteins and reducing inflammatory responses.
Dosage
Patient Age | Standard Dosage | For Acute Inflammation |
---|---|---|
Adults | 1-2 tablets 3× daily | 2 tablets 4× daily |
Children 12+ | 1 tablet 2× daily | 1 tablet 3× daily |
Take Kotase Tablet on empty stomach, 1 hour before or 2 hours after meals for anti-inflammatory effects. With meals for digestive support.
Duration of Action
Kotase begins working within 2-4 hours of administration. Anti-inflammatory effects typically peak at 6-8 hours and last for 8-12 hours. For acute conditions, improvement is usually seen within 24-48 hours. Chronic inflammatory conditions may require 1-2 weeks of consistent use for optimal benefits.
Side Effects
Most patients tolerate Kotase well. Occasional mild gastrointestinal upset, nausea, or diarrhea may occur, especially when starting treatment. Rare allergic reactions include skin rash or itching. Taking with food can minimize digestive discomfort.
Warning
Discontinue Kotase at least 2 weeks before scheduled surgery due to potential bleeding risk. Avoid if allergic to pineapple or other proteolytic enzymes. Not recommended for patients with active peptic ulcers or bleeding disorders. Consult healthcare provider if symptoms worsen or persist.
Pregnancy and Breastfeeding
Limited safety data exists for Kotase during pregnancy. Use only if clearly needed and benefits outweigh potential risks. Consult healthcare provider before taking during breastfeeding. Generally avoided during first trimester unless specifically recommended by a physician.
Interaction
- May enhance effects of anticoagulant medications
- Could increase absorption of certain antibiotics
- Possible interaction with blood pressure medications
- May affect effectiveness of some chemotherapy drugs
- Potential increased bleeding risk with NSAIDs or aspirin
Precaution
Use cautiously in patients with bleeding disorders, kidney disease, or liver impairment. Monitor patients taking anticoagulants closely. Discontinue if unusual bleeding or bruising occurs. Store in cool, dry place away from direct sunlight and moisture.
Important Information
Kotase is generally safe for long-term use under medical supervision. Take consistently for chronic conditions but allow periodic breaks as advised by healthcare provider. Natural enzyme therapy may take longer than conventional anti-inflammatory drugs to show full effects. Maintain adequate hydration while taking this medication.
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