Cefulvin Suspension contains Griseofulvin, an antifungal medication specifically designed to treat fungal infections of the skin, hair, and nails. This oral suspension form provides effective treatment for dermatophyte infections that are difficult to treat with topical medications alone.
Uses
Cefulvin Suspension treats fungal infections caused by dermatophytes including ringworm of the scalp (tinea capitis), body (tinea corporis), groin (tinea cruris), and feet (athlete’s foot). It’s particularly effective for nail fungal infections and severe skin fungal infections that don’t respond to topical treatments.
Benefits
- Effectively treats deep-seated fungal infections
- Penetrates hair follicles and nail beds
- Provides systemic antifungal action
- Prevents spread of fungal infections
- Suitable for pediatric patients
- Liquid form ensures accurate dosing
- Treats infections resistant to topical therapy
- Reduces recurrence rates of fungal infections
- Well-absorbed oral formulation
How It Works
Griseofulvin disrupts fungal cell division by binding to keratin in skin, hair, and nails, making these tissues resistant to fungal invasion. It interferes with fungal microtubule function, preventing proper cell division and growth. The medication concentrates in keratin-rich tissues, providing targeted antifungal action.
Dosage
Patient Weight | Daily Dosage | Treatment Duration |
---|---|---|
Children 15-25 kg | 5-10 ml daily | 4-6 weeks |
Adults >25 kg | 10-20 ml daily | 6-12 weeks |
Take Cefulvin Suspension with fatty meals to enhance absorption. Shake well before each use. Dosage depends on infection severity and location.
Duration of Action
Cefulvin Suspension begins working within days of starting treatment, but visible improvement may take 2-4 weeks. Hair infections typically require 4-6 weeks of treatment, while nail infections may need 6-12 months. The medication remains in keratin tissues for weeks after discontinuation.
Side Effects
Common side effects include headache, nausea, vomiting, and diarrhea. Some patients experience dizziness, fatigue, or skin rash. Photosensitivity may occur, making skin more sensitive to sunlight. Rare but serious effects include liver problems or severe allergic reactions.
Warning
Cefulvin Suspension may cause liver toxicity requiring periodic liver function monitoring during prolonged treatment. Avoid alcohol consumption during therapy. This medication can reduce effectiveness of oral contraceptives. Seek medical attention for persistent nausea, yellowing of skin/eyes, or severe rash.
Pregnancy and Breastfeeding
Cefulvin Suspension is contraindicated during pregnancy due to potential teratogenic effects. Women of childbearing age should use effective contraception during treatment and for one month after completion. Griseofulvin passes into breast milk; breastfeeding should be avoided during treatment.
Interaction
- Reduces effectiveness of oral contraceptives and warfarin
- May interact with phenobarbital, reducing Griseofulvin levels
- Alcohol may cause disulfiram-like reactions
- Potential interaction with cyclosporine
- May alter effects of certain diabetes medications
Precaution
Use with caution in patients with liver disease, lupus, or porphyria. Avoid prolonged sun exposure and use sunscreen. Regular liver function tests may be needed during extended treatment. Inform healthcare providers about all medications before starting Cefulvin Suspension.
Important Information
Cefulvin Suspension requires completion of the full treatment course even after symptoms improve to prevent recurrence. Store at room temperature, away from light and moisture. Shake well before each dose. Treatment success depends on consistent daily dosing and good hygiene practices to prevent reinfection.
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