Dogrel 75mg Tablet (Clopidogrel) x28

Dogrel 75mg Tablet contains Clopidogrel, an antiplatelet medication that prevents blood clots. This medication reduces the risk of heart attack, stroke, and other cardiovascular events in patients with coronary artery disease, peripheral arterial disease, or recent stroke.

Uses

Dogrel 75mg Tablet prevents blood clots in patients with atherosclerotic cardiovascular disease. It’s prescribed for secondary prevention after heart attack, stroke, or established peripheral arterial disease. Dogrel is also used with aspirin in acute coronary syndromes and after coronary stent placement.

Benefits

• Significantly reduces risk of recurrent heart attacks
• Prevents ischemic strokes and cardiovascular death
• Reduces risk of blood clots in coronary arteries
• Improves outcomes after coronary stent procedures
• Prevents clot formation in peripheral arteries
• Reduces need for revascularization procedures
• Well-established safety profile with long-term use
• Once-daily dosing improves medication compliance
• Effective alternative for aspirin-intolerant patients

How It Works

Dogrel 75mg Tablet irreversibly blocks P2Y12 receptors on platelets, preventing platelet aggregation and clot formation. Unlike aspirin, Clopidogrel works through a different pathway, making it effective in patients who don’t respond well to aspirin or need additional antiplatelet protection.

Dosage

Take Dogrel with or without food at the same time each day. Swallow tablets whole with water.

Duration of Action

Dogrel 75mg Tablet begins working within hours, with maximum antiplatelet effects achieved within 3-7 days of regular dosing. The antiplatelet effect persists for 5-7 days after discontinuation as new platelets are gradually produced. This irreversible binding requires medication discontinuation before planned surgeries.

Side Effects

Common side effects include easy bruising, minor bleeding, and gastrointestinal upset. Some patients experience headache, dizziness, or rash. Serious bleeding events are rare but can occur. Contact healthcare provider for unusual bleeding, severe bruising, or signs of internal bleeding.

Warning

Dogrel 75mg Tablet increases bleeding risk and should be discontinued before elective surgery. Do not stop suddenly without medical supervision as this increases clot risk. Some patients may not respond to Clopidogrel due to genetic variations. Seek immediate medical attention for signs of serious bleeding or allergic reactions.

Pregnancy and Breastfeeding

Limited data exists on Dogrel use during pregnancy. Use only if potential benefits justify risks to the fetus. Clopidogrel may pass into breast milk. Discuss with healthcare provider before breastfeeding while taking this medication.

Interaction

• Increased bleeding risk with anticoagulants and other antiplatelets
• Proton pump inhibitors may reduce Dogrel effectiveness
• May enhance effects of certain pain medications
• Possible interaction with some antidepressants
• CYP2C19 inhibitors may affect drug metabolism
• May increase bleeding risk with herbal supplements like garlic or ginkgo

Precaution

Use cautiously in patients with bleeding disorders, active ulcers, or severe liver impairment. Monitor for signs of bleeding during treatment. Inform all healthcare providers and dentists about Dogrel use before procedures. Patients with reduced CYP2C19 function may require alternative therapy.

Important Information

Dogrel 75mg Tablet is typically prescribed for long-term use. Regular follow-up appointments are essential to monitor effectiveness and side effects. Carry medical identification indicating antiplatelet therapy. Avoid activities with high injury risk. Store at room temperature away from moisture and heat. Do not share medication with others.