Jawaclox Drop is a specialized antibiotic formulation combining ampicillin and cloxacillin, designed specifically for neonates. This dual-action medication effectively treats various bacterial infections in newborns, offering broad-spectrum coverage against both gram-positive and gram-negative bacteria.
Uses
Jawaclox Drop is prescribed for treating bacterial infections in neonates, including skin infections, respiratory tract infections, urinary tract infections, and sepsis. It’s particularly effective against penicillin-resistant staphylococcal infections and other common neonatal bacterial pathogens.
Benefits
- Provides broad-spectrum antibacterial coverage
- Effective against penicillin-resistant bacteria
- Specially formulated for neonatal use
- Quick onset of action against infections
- Good safety profile for newborns
- Convenient drop formulation for accurate dosing
How It Works
The combination of ampicillin and cloxacillin works by inhibiting bacterial cell wall synthesis. Ampicillin targets gram-negative bacteria, while cloxacillin is particularly effective against penicillinase-producing gram-positive organisms. This dual mechanism ensures comprehensive coverage against various bacterial infections.
Duration of Action
Jawaclox Drop begins working within 1-2 hours after administration. The therapeutic effect typically lasts 6-8 hours, requiring regular dosing as prescribed. Complete treatment duration usually ranges from 5-10 days, depending on the infection type and severity.
Dosage
| Age Group | Weight/Dose | Frequency/Duration |
|---|---|---|
| 0-7 days | < 2 kg / 0.2 ml | Every 12 hours for 5-7 days |
| 8-28 days | 2-4 kg / 0.3 ml | Every 8 hours for 7-10 days |
| > 28 days | > 4 kg / 0.4 ml | Every 6 hours for 7-14 days |
Side Effects
Common side effects may include mild gastrointestinal disturbances, diaper rash, or temporary changes in feeding patterns. While rare, allergic reactions should be monitored closely in neonates.
Warning
Immediate medical attention is required if signs of allergic reaction occur. Monitor for any unusual reactions during the first few doses of Jawaclox Drop.
Pregnancy and Breastfeeding
Not applicable for neonatal formulation. However, mothers who are breastfeeding should inform their healthcare provider as the medication can pass through breast milk.
Interactions
- May interact with probenecid
- Potential interaction with other antibiotics
- Can affect certain laboratory test results
Precautions
Liver and kidney function should be monitored during treatment. Maintain proper hygiene during administration. Store drops in a cool, dry place and discard any unused portion after the recommended period.
Important Information
Complete the full course of Jawaclox Drop as prescribed, even if symptoms improve. Keep regular follow-up appointments with your pediatrician. Monitor your baby’s temperature and feeding patterns during treatment. Contact your healthcare provider immediately if you notice any concerning symptoms.
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