Axerem Tablet Azithromycin 500mg

Axerem Tablet Azithromycin 500mg is a prescription antibiotic medication. It belongs to the macrolide class of antibiotics and is effective against a wide range of bacterial infections. This potent formulation is designed for convenient once-daily dosing in most cases.

Uses

Axerem Tablet treats respiratory tract infections including pneumonia, bronchitis, sinusitis, and pharyngitis/tonsillitis. It also treats skin and soft tissue infections, sexually transmitted infections like chlamydia,syphilis and gonorrhea, and ear infections. Azithromycin is effective for treating typhoid fever and certain atypical mycobacterial infections.

Benefits

• Broad-spectrum antibacterial coverage
• Convenient once-daily dosing
• Short treatment duration for most infections
• High tissue concentration at infection sites
• Extended half-life allowing shorter treatment courses
• Effective against respiratory, skin, and urogenital infections
• Good safety profile compared to other antibiotics
• Excellent tissue penetration

How It Works

Azithromycin binds to the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. This action prevents bacteria from growing and multiplying. Unlike bactericidal antibiotics, Azithromycin is primarily bacteriostatic but can be bactericidal at higher concentrations.

Duration of Action

Azithromycin has an exceptionally long half-life of 68 hours, allowing for once-daily dosing. The drug concentrates in tissues and remains active at infection sites for 5-7 days after the last dose, providing ongoing antibacterial effects after completing treatment.

Dosage

Warnings

Do not use Axerem Tablet if allergic to Azithromycin, Erythromycin, or any macrolide antibiotics. Use caution in patients with liver disease, kidney disease, myasthenia gravis, or prolonged QT interval. Discontinue immediately if signs of allergic reaction occur.

Side Effects

Common side effects include nausea, vomiting, diarrhea, abdominal pain, and headache. Less common effects include heart rhythm abnormalities, elevated liver enzymes, allergic reactions, and hearing changes. Rare but serious side effects include severe diarrhea, liver damage, and severe skin reactions.

Pregnancy and Breastfeeding

Azithromycin is generally considered safe during pregnancy but should be used only when clearly needed. The drug passes into breast milk in small amounts. Consult a healthcare provider before using during pregnancy or while breastfeeding.

Interactions

• Antacids containing aluminum or magnesium (reduced absorption)
• QT-prolonging medications (increased cardiac risk)
• Warfarin (enhanced anticoagulant effect)
• Digoxin (increased digoxin levels)
• Statins (increased risk of muscle problems)
• Ergot derivatives (increased risk of ergotism)
• Nelfinavir (increased azithromycin exposure)

Precautions

Take Axerem Tablet at least 1 hour before or 2 hours after meals for optimal absorption. Complete the entire course as prescribed even if symptoms improve. Take at the same time each day to maintain consistent blood levels. Do not share this medication with others regardless of similar symptoms.

Important Information

Axerem Tablet should only be used for bacterial infections, not viral infections like colds or flu. Unnecessary use increases antibiotic resistance risk. Take exactly as prescribed and complete the full course even if symptoms improve quickly.