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Flagyl 400mg Tablet (Metronidazole) x100

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Flagyl 400mg (Metronidazole) is used for bacterial infections and parasitic infections like intra-abdominal infections, skin infections and Trichomoniasis

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SKU:0040

Flagyl 400mg Tablets contain the antibiotic medication Metronidazole, which is effective in treating a variety of anaerobic bacterial and protozoal infections. This prescription medication is a key component in the management of various conditions, including bacterial vaginosis, trichomoniasis, and intra-abdominal infections.

Uses

Flagyl 400mg Tablets are primarily used to treat the following conditions:

  • Bacterial vaginosis
  • Trichomoniasis (a sexually transmitted infection)
  • Intra-abdominal infections
  • Pelvic inflammatory disease
  • Intra-abdominal abscesses
  • Gastroenteritis caused by Clostridium difficile

Benefits

  • Effectively treats anaerobic bacterial and protozoal infections
  • Helps restore normal vaginal flora in bacterial vaginosis
  • Eradicates Trichomonas parasite in trichomoniasis
  • Manages serious intra-abdominal infections
  • Reduces risk of post-surgical complications
  • Helps eliminate Clostridium difficile in gastroenteritis
  • Prevents recurrence of certain infections
  • Cost-effective antibiotic treatment option

How It Works

Metronidazole disrupts the DNA structure of anaerobic bacteria and protozoans, leading to their death. This mechanism of action makes it particularly effective against organisms that thrive in low-oxygen environments.

Duration of Action

Symptom improvement is typically seen within 2-3 days of starting Flagyl 400mg treatment. However, it is important to complete the full course of antibiotics as prescribed, usually 7-10 days, to ensure complete eradication of the infection.

Dosage

Bacterial vaginosis: 400mg twice daily for 7 days Trichomoniasis: 2g as a single dose Intra-abdominal infections: 500mg three times daily for 7-10 days Clostridium difficile-associated diarrhea: 400mg three times daily for 10 days

Side Effects

Common side effects may include nausea, metallic taste, headache, and gastrointestinal discomfort. Serious side effects are rare but may include allergic reactions, central nervous system effects, and darkening of urine.

Warning

Avoid alcohol consumption during and for 3 days after treatment, as it can cause a disulfiram-like reaction. Discontinue use and seek medical attention if severe side effects occur. Not recommended for patients with certain neurological disorders.

Pregnancy and Breastfeeding

Flagyl 400mg Tablets are generally considered safe for use during pregnancy and breastfeeding when prescribed by a healthcare provider. However, the potential risks should be discussed with the doctor, especially during the first trimester of pregnancy.

Interactions

  • May interact with anticoagulants, lithium, and certain antidepressants
  • Can affect the metabolism of alcohol, leading to a disulfiram-like reaction
  • Possible interaction with certain cancer medications
  • May interact with cholestyramine and colestipol

Important Information

Take Flagyl 400mg Tablets with food to minimize gastrointestinal side effects. Complete the full course of treatment as directed, even if symptoms improve. Store the medication at room temperature, away from moisture and heat. Report any unusual side effects to your healthcare provider.

Category Dosage Instructions
Adults 400 mg three times daily for 7-10 days, depending on the type and severity of the infection.
Elderly Same as adult dosage, though dose adjustment may be required based on tolerance and renal function.
Children (Dose varies by weight and condition) 7.5 mg per kg of body weight, given three times daily. Dosage duration varies by infection type.

How to Use

  1. Take With or After Food: This helps to minimize potential stomach upset.
  2. Do Not Crush or Chew: Swallow the tablet whole with water.
  3. Finish the Full Course: Even if symptoms improve, complete the prescribed course to avoid recurrence of infection.

Important Information

  • Side Effects: Common effects include nausea, metallic taste, stomach upset, and headache. Avoid alcohol during treatment and for at least 48 hours after, as it can cause adverse reactions.
  • Warnings: Not recommended in the first trimester of pregnancy. Use with caution in patients with liver issues.
  • Pregnancy and Breastfeeding: Should be used during pregnancy only if prescribed by a healthcare provider. Generally not recommended during breastfeeding unless advised by a doctor.

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