Kriscet-400 Cimetidine Caplets x20

Kriscet-400 is a medication containing Cimetidine 400mg, an H2 receptor antagonist that reduces stomach acid production. This H2 blocker effectively treats acid-related gastrointestinal disorders including ulcers, GERD, and pathological hypersecretory conditions

Uses

The main uses of Kriscet-400 include:

• Treatment of acid reflux and gastroesophageal reflux disease (GERD)
• Healing and prevention of gastric and duodenal ulcers
• Relief of active duodenal ulcers and associated pain
• Prevention of upper gastrointestinal bleeding in critically ill patients
• Management of pathological hypersecretory conditions like Zollinger-Ellison syndrome

Benefits

Key benefits of taking Kriscet-400 include:

• Effectively reduces the amount of acid produced by the stomach
• Promotes healing of existing ulcers and prevents new ones from forming
• Relief from acid reflux, heartburn, and associated discomfort
• Helps prevent stress-related upper GI bleeding in high-risk patients
• Improves overall symptoms and quality of life for those with acid disorders
• Offers rapid symptom relief within hours of administration
• Helps maintain remission of healed ulcers
• Reduces risk of complications from acid-related conditions

How It Works

Kriscet-400 works by reversibly binding to and blocking histamine H2 receptors in the stomach lining. This inhibits histamine’s action on parietal cells, significantly reducing gastric acid secretion and creating an optimal environment for ulcer healing and symptom relief.

Dosage

Take Kriscet-400 with or without food. Adjust dosage in patients with kidney impairment as directed by healthcare provider.

Duration of Action

Kriscet-400 begins reducing acid production within 1-2 hours of administration. Peak effects occur within 2-4 hours and acid suppression lasts approximately 6-8 hours. For ulcer healing, therapeutic effects typically become noticeable within 1-2 weeks of regular use.

Side Effects

Common side effects include headache, diarrhea, constipation, dizziness, skin rash, and muscle pain. Rare but serious effects may include confusion, gynecomastia (breast enlargement), blood disorders like agranulocytosis, or liver problems requiring immediate medical attention.

Warning

Avoid Kriscet-400 if allergic to cimetidine or other H2 blockers. Use with extreme caution in patients with kidney disease, lung disease, or G6PD deficiency. Avoid alcohol consumption and limit high-protein intake during treatment. Discontinue immediately if pregnancy occurs.

Pregnancy and Breastfeeding

Kriscet-400 should be avoided during pregnancy unless absolutely necessary and benefits outweigh potential risks. Cimetidine passes into breast milk and may affect nursing infants. Consult healthcare provider before use during breastfeeding to weigh risks and benefits.

Interaction

• May increase blood levels of warfarin, increasing bleeding risk
• Can enhance effects of certain antiarrhythmic medications
• May interact with anticonvulsants, altering their effectiveness
• Possible interaction with benzodiazepines, increasing sedation
• Can affect absorption of certain antifungal medications
• May alter effectiveness of some chemotherapy drugs

Precaution

Monitor kidney function regularly during long-term use. Elderly patients may require dosage adjustments due to decreased kidney function. Avoid abrupt discontinuation to prevent acid rebound. Regular blood tests may be needed to monitor for rare blood disorders. Inform all healthcare providers about Kriscet-400 use.

Important Information

Take Kriscet-400 exactly as prescribed by your healthcare provider. Do not combine with other acid-reducing medications without medical supervision. Report any worsening symptoms, unusual bleeding, confusion, or persistent side effects immediately. Store at room temperature away from moisture and heat. Complete the full course even if symptoms improve early.