Panadol Night Tablet (Paracetamol & Diphenhydramine)

Panadol Night Tablet combines Paracetamol (500 mg) and Diphenhydramine (25 mg) for nighttime pain relief with sleep aid. This dual-action formula provides effective pain and fever relief while helping users fall asleep naturally.

Uses

Panadol Night Tablet treats pain and fever while promoting sleep. It’s effective for headaches, muscle aches, toothaches, backaches, and minor arthritis pain that interfere with sleep. The medication helps break the pain-sleep cycle commonly experienced with nighttime discomfort.

Benefits

• Provides effective pain and fever relief
• Aids natural sleep induction
• Combines analgesic and sedating effects
• Reduces nighttime pain interruptions
• Improves overall sleep quality
• Non-habit forming sleep assistance
• Suitable for occasional use
• Helps restore normal sleep patterns
• Gentle on the stomach when taken as directed

How It Works

Paracetamol reduces pain and fever by inhibiting prostaglandin synthesis in the brain. Diphenhydramine, an antihistamine, causes drowsiness by blocking histamine receptors and crossing the blood-brain barrier. This combination addresses both pain management and sleep difficulties simultaneously.

Dosage

Take 20-30 minutes before desired bedtime with water. Do not exceed recommended dose or take during daytime hours.

Duration of Action

Panadol Night begins working within 30-60 minutes of administration. Pain relief typically lasts 4-6 hours, while sedating effects may persist for 6-8 hours. Most users fall asleep within 1-2 hours of taking the medication.

Side Effects

Common side effects include drowsiness extending into the next day, dry mouth, blurred vision, and constipation. Some users experience dizziness, confusion, or urinary retention. Rare but serious effects include liver damage from paracetamol overdose or severe allergic reactions.

Warning

Use only at bedtime and when able to sleep for 7-8 hours. Do not drive or operate machinery after taking Panadol Night. Avoid alcohol consumption. Do not exceed recommended dose as paracetamol overdose can cause severe liver damage. Not suitable for daily long-term use.

Pregnancy and Breastfeeding

Paracetamol is generally safe during pregnancy when used as directed. However, diphenhydramine should be avoided, especially in the third trimester. Consult healthcare provider before use. Both ingredients pass into breast milk and may cause drowsiness in nursing infants.

Interaction

• Enhanced sedation when combined with alcohol or other sedatives
• May increase effects of blood-thinning medications
• Possible reduced effectiveness with certain seizure medications
• May interact with monoamine oxidase inhibitors (MAOIs)
• Could enhance effects of other antihistamines or sleep aids

Precaution

Use cautiously in elderly patients who may be more sensitive to diphenhydramine effects. Avoid in patients with enlarged prostate, narrow-angle glaucoma, or breathing problems. Those with liver disease should consult a doctor before use. Discontinue if next-day drowsiness persists.

Important Information

Panadol Night is for occasional use only and not intended for chronic insomnia management. If pain or sleep problems persist beyond a few days, consult a healthcare provider. Store at room temperature away from children. Do not use with other paracetamol-containing products to avoid overdose. Check all medications for paracetamol content before combining.