Resthrotec 75mg ( Diclofenac+Misoprostol)

Resthrotec 75mg tablets contain a combination of diclofenac sodium 75mg (a nonsteroidal anti-inflammatory drug) and misoprostol 200mcg (a gastrointestinal mucosal protective prostaglandin E1 analog).

Uses

Resthrotec 75mg is used for reducing the risk of NSAID-induced gastric ulcers in patients at risk who require diclofenac therapy.

Benefits

Resthrotec 75mg offers dual benefits:

• Diclofenac for relief of pain and inflammation
• Misoprostol to decrease the chance of developing NSAID-induced gastric ulcers

Mechanism of Action

• Diclofenac inhibits COX enzymes leading to decreased prostaglandin synthesis resulting in anti-inflammatory, analgesic, and antipyretic effects.
• Misoprostol enhances defenses of the gastric mucosal lining.

Together they provide effective pain relief with protection against NSAID-associated gastric ulcers.

Dosage

• Recommended dose: 1 tablet twice daily with food
• Swallow tablets whole – do not split, crush or chew
• Duration as directed by physician (usually 7-14 days)

Side Effects

Possible side effects include:

• Abdominal pain, diarrhea, dyspepsia
• Dizziness, headache
• Nausea, vomiting
• Flatulence, constipation
• Increased risk of uterine contractions in pregnancy

Warnings

• Increased risk of cardiovascular events with prolonged NSAID use
• Avoid use in late pregnancy due to risk of early labor and fetal adverse effects
• Contraindicated in patients hypersensitive to diclofenac or misoprostol

Important Information

• Take with food to reduce stomach upset
• Avoid use with other NSAIDs or salicylates
• Report any signs of ulceration, bleeding or perforation
• Use lowest effective dose for shortest time needed