Zortafen Tablet 50mg contains Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID). This medication effectively reduces pain, inflammation, and fever by inhibiting prostaglandin synthesis. Zortafen provides relief for various inflammatory and painful conditions.
Uses
Zortafen Tablet treats pain and inflammation associated with arthritis, rheumatoid arthritis, osteoarthritis, and musculoskeletal disorders. It’s effective for headaches, dental pain, menstrual cramps, sprains, and post-operative pain. Zortafen also reduces fever and provides symptomatic relief in various inflammatory conditions.
Benefits
- Provides effective pain relief within 30-60 minutes
- Reduces inflammation and swelling significantly
- Offers long-lasting effects lasting 8-12 hours
- Effective for both acute and chronic pain conditions
- Reduces fever and associated discomfort
- Improves mobility in arthritis patients
- Suitable for various types of pain
- Available in convenient oral tablet form
- Cost-effective pain management option
How It Works
Zortafen works by inhibiting cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, which are responsible for prostaglandin production. By blocking these enzymes, Diclofenac reduces prostaglandin levels, thereby decreasing inflammation, pain sensation, and fever response at the affected sites.
Dosage
Condition | Standard Dosage | Maximum Daily Dosage |
---|---|---|
Adults | 50mg 2-3× daily | 150mg daily |
Elderly | 25-50mg 2× daily | 100mg daily |
Take Zortafen with food or milk to reduce stomach irritation. Swallow tablets whole with a full glass of water.
Duration of Action
Zortafen begins working within 30-60 minutes of administration. Peak pain relief occurs at 2-3 hours and lasts for 8-12 hours. For inflammatory conditions, maximum anti-inflammatory effects may take 1-2 weeks of regular use to develop fully.
Side Effects
Common side effects include stomach upset, nausea, heartburn, and diarrhea. Some patients experience dizziness, headache, or skin rash. Serious side effects may include stomach ulcers, bleeding, kidney problems, or allergic reactions requiring immediate medical attention.
Warning
Zortafen increases risk of serious cardiovascular events including heart attack and stroke. Risk of serious gastrointestinal bleeding, ulceration, and perforation exists. Use lowest effective dose for shortest duration possible. Not recommended for patients with active peptic ulcer disease or recent cardiovascular events.
Pregnancy and Breastfeeding
Avoid Zortafen during pregnancy, especially in the third trimester, as it may cause harm to the fetus or complications during delivery. Use during breastfeeding is generally not recommended as small amounts pass into breast milk. Consult healthcare provider for safer alternatives.
Interaction
- Increased bleeding risk when combined with anticoagulants
- May reduce effectiveness of blood pressure medications
- Possible kidney damage when used with ACE inhibitors
- Enhanced toxicity when combined with methotrexate
- May increase lithium levels in blood
- Reduced effectiveness of diuretics and some heart medications
Precaution
Use with extreme caution in patients with history of stomach ulcers, kidney disease, liver problems, or heart conditions. Monitor blood pressure regularly during treatment. Avoid alcohol consumption while taking Zortafen. Elderly patients require lower doses and careful monitoring for adverse effects.
Important Information
Zortafen is for short-term use unless specifically prescribed for chronic conditions under medical supervision. Take with food to minimize stomach irritation. Do not exceed recommended dosage or duration. Stop taking and seek medical attention if experiencing stomach pain, black stools, or signs of allergic reaction. Store at room temperature away from moisture and heat.
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